Evidence map›Paper›PMID 29948835›Full record

GuidelineInternal and emergency medicine2019

Guidelines for the management of osteoporosis and fragility fractures.

Ranuccio Nuti, Maria Luisa Brandi, Giovanni Checchia, Ombretta Di Munno, Ligia Dominguez, Paolo Falaschi, Carmelo Erio Fiore, Giovanni Iolascon, Stefania Maggi, Raffaella Michieli and 7 more

Abstract readPractice Guideline
In one paragraph

Guideline in Internal and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
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  9. Trial
  10. Romosozumab improves microarchitecture as assessed by tissue thickness-adjusted trabecular bone score in postmenopausal women with osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Trial
  11. Pro-Osteogenic Effect of the Nutraceutical BlastiMin ComplexInternational journal of molecular sciences · 2024
    Trial
  12. Trial
  13. Trial
  14. Article
  15. Clinical insights into the association between chronic liver disease and osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  16. Review
  17. Application and prospects of nanomaterials in osteoporosis treatment.International journal of pharmaceutics: X · 2026
    Review
  18. Review
  19. Review
  20. Article

105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ranuccio NutiSIMI, (Italian Society of Internal Medicine), Rome, Italy.
Maria Luisa BrandiSIE (Italian Society of Endocrinology), Rome, Italy.
Giovanni ChecchiaSIMFER (Italian Society of Physical and Rehabilitation Medicine), Rome, Italy.
Ombretta Di MunnoSIR (Italian Society of Rheumatology), Milan, Italy.
Ligia DominguezSIOMMMS (Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases), Rome, Italy.
Paolo FalaschiSIGG (Italian Society of Gerontology and Geriatrics), Firenze, Italy.
Carmelo Erio FioreSIMI, (Italian Society of Internal Medicine), Rome, Italy.
Giovanni IolasconSIMFER (Italian Society of Physical and Rehabilitation Medicine), Rome, Italy.
Stefania MaggiSIGG (Italian Society of Gerontology and Geriatrics), Firenze, Italy.
Raffaella MichieliSIMG (Italian Society of General Medicine and of Primary Care), Firenze, Italy.
Silvia MigliaccioSIE (Italian Society of Endocrinology), Rome, Italy.
Salvatore MinisolaSIMI, (Italian Society of Internal Medicine), Rome, Italy. salvatore.minisola@uniroma1.it.ORCID http://orcid.org/0000-0001-6525-0439
Maurizio RossiniSIR (Italian Society of Rheumatology), Milan, Italy.
Giuseppe SessaSIOT (Italian Society of Orthopaedics), Genoa, Italy.
Umberto TarantinoSIOT (Italian Society of Orthopaedics), Genoa, Italy.
Antonella ToselliSIMG (Italian Society of General Medicine and of Primary Care), Firenze, Italy.
Giovanni Carlo IsaiaSIOMMMS (Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases), Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this document, a result of the harmonisation and revision of Guidelines published separately by the SIMFER, SIOMMMS/SIR, and SIOT associations, is to provide practical indications based on specific levels of evidence and various grades of recommendations, drawn from available literature, for the management of osteoporosis and for the diagnosis, prevention, and treatment of fragility fractures. These indications were discussed and formally approved by the delegates of the Italian Scientific Associations involved in the project (SIE, SIGG, SIMFER, SIMG, SIMI, SIOMMMS, SIR, and SIOT).

Indexed as

Bone DensityHumansItalyOsteoporosisOsteoporotic FracturesFracturesOsteoporosisTherapy

Identifiers

PMID29948835
PMCPMC6329834

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.