Evidence map›Paper›PMID 29948806›Full record

ArticleJournal of general internal medicine2018

Incidence of Acute Cardiovascular Event After Acute Exacerbation of COPD.

Tadahiro Goto, Yuichi J Shimada, Mohammad Kamal Faridi, Carlos A Camargo, Kohei Hasegawa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of general internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Tadahiro GotoDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA. tag695@mail.harvard.edu.
Yuichi J ShimadaCardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Mohammad Kamal FaridiDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Kohei HasegawaDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.

Funding

Comparative Effectiveness Research on Hospital Readmissions for COPDR01HS023305 · AHRQ · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2015 to 2019
$1.1M
AHRQ HHS R01 HS023305
6 · The paper itself

Abstract

backgroundThere is a lack of comprehensive view of the association between acute exacerbation of COPD (AECOPD) and the risk of acute cardiovascular events.

objectiveTo determine the association of AECOPD with 30-day and 1-year incidences of acute cardiovascular event.

designSelf-controlled case series analysis using population-based datasets from three US states from 2005 through 2011.

participantsPatients aged ≥ 40 years with AECOPD. MAIN MEASURES: The primary outcome was a composite of an ED visit or hospitalization for acute cardiovascular events, including acute myocardial infarction, heart failure, atrial fibrillation, pulmonary embolism, and stroke. We compared the incidence of each patient's acute cardiovascular event during the first 30-day period before the index AECOPD (30-day reference period) in comparison with that during the 30-day period after the index AECOPD. Likewise, with the 1-year period before the index AECOPD as reference, we also estimated incidence rate ratios (IRRs) for each patient's outcomes during 1-year period after the index AECOPD. KEY

resultsOverall, there were 362,867 patients with an ED visit or hospitalization for AECOPD. Compared with the 30-day reference period, the incidence of acute cardiovascular event in the 30-day period after the AECOPD was significantly higher (IRR, 1.34; 95%CI, 1.30-1.39; P < 0.001). Likewise, compared with the 1-year reference period, the incidence during the 1-year period after the AECOPD was also higher (IRR, 1.20; 95%CI, 1.18-1.22; P < 0.001). For each of acute cardiovascular conditions, the associations remained significant (all P < 0.05).

conclusionsAECOPD was associated with increased 30-day and 1-year incidences of acute cardiovascular event.

Indexed as

Cardiovascular DiseasesPulmonary Disease, Chronic ObstructiveAcute DiseaseAgedCorrelation of DataFemaleHospitalizationHumansIncidenceMaleMiddle AgedOutcome Assessment, Health CareRisk AssessmentRisk FactorsSymptom Flare UpUnited Statesacute exacerbation of COPDcardiovascular diseasesCOPD

Identifiers

PMID29948806
PMCPMC6108996

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.