Evidence map›Paper›PMID 29948641›Full record

ArticleMolecular imaging and biology2019

[

Claire Provost, Laura Rozenblum-Beddok, Valérie Nataf, Fatiha Merabtene, Aurélie Prignon, Jean-Noël Talbot

Open access · greenAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. PotentialFrontiers in oncology · 2022
    Article
  2. Article
  3. Evaluation of Integrin αDiagnostics (Basel, Switzerland) · 2021
    Article
  4. Review
  5. Review
  6. [European journal of nuclear medicine and molecular imaging · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Claire ProvostLaboratoire d'Imagerie Moléculaire Positonique (LIMP), UMS 28, UPMC - Sorbonne Universités, Paris, France. claire.provost@upmc.fr.ORCID http://orcid.org/0000-0002-4390-4486
Laura Rozenblum-BeddokLaboratoire d'Imagerie Moléculaire Positonique (LIMP), UMS 28, UPMC - Sorbonne Universités, Paris, France.
Valérie NatafLaboratoire d'Imagerie Moléculaire Positonique (LIMP), UMS 28, UPMC - Sorbonne Universités, Paris, France.
Fatiha MerabtenePlateforme d'Histomorphologie Service d'Anatomie Pathologique, Hôpital Saint Antoine, AP-HP, Paris, France.
Aurélie PrignonLaboratoire d'Imagerie Moléculaire Positonique (LIMP), UMS 28, UPMC - Sorbonne Universités, Paris, France.
Jean-Noël TalbotLaboratoire d'Imagerie Moléculaire Positonique (LIMP), UMS 28, UPMC - Sorbonne Universités, Paris, France.
Sorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate positron emission tomography (PET) imaging with [ PROCEDURES: Mice bearing U87MG human GB cells line were parted into five groups of five mice each. One group was imaged at baseline before the treatment phase; another group was treated with bevacizumab (BVZ), another group with temozolomide (TMZ), another group with both agents, and the last one was the control group. Tumors growth and biological properties were evaluated by caliper measurements and PET imaging at three time points (baseline, during treatment t1 = 4-6 days and t2 = 10-12 days). At the end of the study, tumors were counted and analyzed by immunohistochemistry (CD31 to evaluate microvessel density).

resultsThe tumor volume assessed by caliper measurements was significantly greater at t1 in the control group than in the TMZ + BVZ-treated group or in the BVZ-treated group. At t2, tumor volume of all treated groups was significantly smaller than that of the control group. [

conclusions[

Indexed as

Positron-Emission TomographyAnimalsBevacizumabBrain NeoplasmsCell Line, TumorCell ProliferationDisease Models, AnimalFluorodeoxyglucose F18Gallium RadioisotopesGlioblastomaHumansMiceOligopeptidesTemozolomideTissue DistributionTreatment Outcomearginyl-glycyl-aspartic acidBevacizumabFluorodeoxyglucose F18Gallium-68Gallium RadioisotopesOligopeptidesTemozolomide[18F]FDG[68Ga]RGDAngiogenesisBevacizumabIntegrins αvβ3PETTemozolomide

Identifiers

PMID29948641
OpenAlexW2808586184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.