Evidence map›Paper›PMID 29948577›Full record

ArticlePurinergic signalling2018

Increased Ap

María J Pérez de Lara, Ana Guzmán-Aranguez, Rosa Gómez-Villafuertes, Javier Gualix, María Teresa Miras-Portugal, Jesús Pintor

Open access · bronzeAbstract read
In one paragraph

Article in Purinergic signalling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

María J Pérez de LaraDepartment of Biochemistry and Molecular Biology IV, Faculty of Optics and Optometry, Complutense University of Madrid, c/Arcos de Jalón 118, 28037, Madrid, Spain.
Ana Guzmán-AranguezDepartment of Biochemistry and Molecular Biology IV, Faculty of Optics and Optometry, Complutense University of Madrid, c/Arcos de Jalón 118, 28037, Madrid, Spain.
Rosa Gómez-VillafuertesDepartment of Biochemistry and Molecular Biology IV, Faculty of Veterinary, Complutense University of Madrid, Av/ Puerta del Hierro s/n, 28040, Madrid, Spain.
Javier GualixDepartment of Biochemistry and Molecular Biology IV, Faculty of Veterinary, Complutense University of Madrid, Av/ Puerta del Hierro s/n, 28040, Madrid, Spain.
María Teresa Miras-PortugalDepartment of Biochemistry and Molecular Biology IV, Faculty of Veterinary, Complutense University of Madrid, Av/ Puerta del Hierro s/n, 28040, Madrid, Spain.
Jesús PintorDepartment of Biochemistry and Molecular Biology IV, Faculty of Optics and Optometry, Complutense University of Madrid, c/Arcos de Jalón 118, 28037, Madrid, Spain. jpintor@ucm.es.
Universidad Complutense de Madrid · ES

Funding

Ministerio de Economía y Competitividad BFU2014-53654-PMinisterio de Economía y Competitividad DI-15-07639Ministerio de Economía y Competitividad SAF-2013-44416-RMinisterio de Economía y Competitividad SAF2016-77084RMinisterio de Sanidad, Servicios Sociales e Igualdad RD12/0034/0001Ministerio de Sanidad, Servicios Sociales e Igualdad RD16/0008/0017
6 · The paper itself

Abstract

The pathogenesis of glaucoma involves numerous intracellular mechanisms including the purinergic system contribution. Furthermore, the presence and release of nucleotides and dinucleotides during the glaucomatous damage and the maintenance of degradation machinery through ecto-nucleotidase activity are participating in the modulation of the suitable extracellular complex balance. The aim of this study was to investigate the levels of diadenosine tetraphosphate (Ap

Indexed as

AnimalsDinucleoside PhosphatesGlaucomaMaleMiceMice, Inbred C57BLMice, Inbred DBAPhosphoric Diester HydrolasesPyrophosphatasesRetinadiadenosine tetraphosphateDinucleoside Phosphatesectonucleotide pyrophosphatase phosphodiesterase 1Phosphoric Diester HydrolasesPyrophosphatasesAp4ADBA/2JEcto-nucleotidasesGlaucomaNPP1NucleotidesRetina

Identifiers

PMID29948577
PMCPMC6107467
OpenAlexW2806620944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.