Evidence map›Paper›PMID 29948455›Full record

ArticleLasers in medical science2019

Promotion of wound healing through low-fluence ablative fractional laser treatment in diabetic mice.

Han Na Lee, Jung Min Bae, Bon Cheol Leo Goo, Young Min Park

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Therapeutic effect of low-level 10,600 nm COLasers in medical science · 2025
    Article
  2. [Opinion on the photoelectric therapy of scars].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Han Na LeeDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Jung Min BaeDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Bon Cheol Leo GooNaum Clinic, Seoul, South Korea.
Young Min ParkDepartment of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpodae-ro, Seocho-gu, Seoul, 06591, South Korea. yymmpark6301@hotmail.com.
St. Vincent's Hospital · KRSeoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic ulcers are a significant cause of morbidity in diabetic patients, which can greatly affect a patient's quality of life. While numerous methods have been developed to promote and enhance wound healing in diabetic patients, a convenient, effective treatment for diabetic ulcers has yet to be established. Here, we demonstrate the promotion of wound healing using a low-fluence (2 mJ/spot) ablative fractional laser (AFL) treatment in diabetic mice. Treatment was shown to confer increases in mRNA expression and in protein abundance of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), along with decreases in mRNA expression and protein abundance of transforming growth factor beta (TGF-β). Taken together, these results suggest that low-fluence AFL treatment can be used to promote healing in chronic diabetic wounds.

Indexed as

Laser TherapyWound HealingAnimalsDiabetes Mellitus, ExperimentalFibroblast Growth Factor 2MaleMiceRNA, MessengerTransforming Growth Factor betaVascular Endothelial Growth Factor AFibroblast Growth Factor 2RNA, MessengerTransforming Growth Factor betaVascular Endothelial Growth Factor ADiabeticsFractional laserRegenerationWound healingWound repair

Identifiers

PMID29948455
OpenAlexW2808008328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.