Evidence map›Paper›PMID 29948443›Full record

ArticleClinical and experimental nephrology2018

GFR-estimation by serum creatinine during glucocorticosteroid therapy.

Emil den Bakker, Berend Koene, Joanna A E van Wijk, Isabelle Hubeek, Reinoud Gemke, Arend Bökenkamp

Abstract read
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In one paragraph

Article in Clinical and experimental nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emil den BakkerDepartment of Pediatric Nephrology, VU University Medical Center, De Boelelaan 1112, 1081 HV, Amsterdam, The Netherlands. e.denbakker@outlook.com.
Berend KoeneDepartment of Pediatric Nephrology, VU University Medical Center, De Boelelaan 1112, 1081 HV, Amsterdam, The Netherlands.
Joanna A E van WijkDepartment of Pediatric Nephrology, VU University Medical Center, De Boelelaan 1112, 1081 HV, Amsterdam, The Netherlands.
Isabelle HubeekDepartment of Clinical Chemistry, VU University Medical Centre, Amsterdam, The Netherlands.
Reinoud GemkeDepartment of Pediatrics, VU University Medical Centre, Amsterdam, The Netherlands.
Arend BökenkampDepartment of Pediatric Nephrology, VU University Medical Center, De Boelelaan 1112, 1081 HV, Amsterdam, The Netherlands.
Amsterdam UMC Location VUmc · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile glucocorticosteroids (GCS) are widely used in patients with kidney disease, little is known about their effect on serum creatinine, the most commonly used endogenous marker of kidney function.

methodsWe assessed the effect of GCS on the relationship between estimated GFR using the Schwartz equation (eGFR) and measured GFR using a single-injection inulin clearance (Cin) in children both in a paired analysis and a cross-sectional study. Primary outcome variable was the difference between eGFR and Cin (ΔGFR) in a paired analysis involving 22 patients during and off GCS treatment (mean GFR 103.8 ml/min/1.73 m

resultsThe paired analysis showed no significant difference in ΔGFR with or without GCS [- 23 (SD 53) vs. - 9 (SD 41) ml/min/1.73 m

conclusionGCS use had no significant effect on serum creatinine as a marker for kidney function in a mixed population of renal outpatient clinic children.

Indexed as

Glomerular Filtration RateBayes TheoremChildChild, PreschoolCreatinineCross-Sectional StudiesFemaleHumansMaleRetrospective StudiesCreatinineCreatinineEstimated GFRGlucocorticosteroids

Identifiers

PMID29948443
OpenAlexW2806874846

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.