Evidence map›Paper›PMID 29948280›Full record

ArticleClinical oral investigations2019

Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study.

Esa Färkkilä, Riina Rautemaa-Richardson, Anniina Färkkilä, Lotta Grönholm, Anneli Lauhio

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Article in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Esa FärkkiläDepartment of Oral and Maxillofacial Surgery, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4 E, P.O. Box 220, 00029, HUS, Helsinki, Finland. esa.farkkila@helsinki.fi.
Riina Rautemaa-RichardsonDivision of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M23 9LT, UK.
Anniina FärkkiläDepartment of Obstetrics and Gynaecology, Helsinki University Hospital and University of Helsinki, Tukholmankatu 8, P.O. Box 20, 00029, HUS, Helsinki, Finland.
Lotta GrönholmDepartment of Oncology, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, P.O. Box 180, 00029, HUS, Helsinki, Finland.
Anneli LauhioDepartment of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, Nordenskiöldinkatu 20, building 5 3rd floor, P.O. BOX 348, 00029, HUS, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance. MATERIALS AND

methodsA database search of all referrals to the Oral and Maxillofacial Diseases unit of HUH in 2009 was performed. Of the 2807 referrals, 408 were due to a known or suspected OIPS. The electronic patient records of these patients were analysed for patient demographics, lifestyle factors, radiological findings and clinical oral findings. Risk factors for OIPS were analysed using logistic regression and using the significant factors in univariate analyses in the multivariate models.

resultsThe mean age of the patients was 58 years. Most patients (n = 270, 66%) were referred due to upcoming cancer or other immunosuppressive therapy. The majority (n = 314, 77%) were diagnosed with one or more OIPS. In univariate analyses, smoking (OR 3.2, 95% CI 1.6-6.4; p = 0.0006), male gender (OR 1.7, 95% CI 1.1-2.8; p = 0.02), excessive alcohol use (OR 3.0, 95% 1.1-7.9; p = 0.03) and irregular dental care (OR 4.8, 95% CI 2.6-8.8; p < 0.0001) were risk factors for OIPS. However, in multivariate analyses, smoking was the only independent risk factor for OIPS (OR 3.6, 95% CI 1.2-11.8; p = 0.02).

conclusionsOIPS are common in patients referred for OIPS clearance, and smoking was identified as an independent behavioural risk factor for them. These findings highlight the burden of disease in this patient group and the importance of smoking cessation encouragement. CLINICAL RELEVANCE: To identify patients at increased risk of OIPS.

Indexed as

AdultAgedAged, 80 and overCohort StudiesFemaleFinlandHumansInfectionsMaleMiddle AgedRisk FactorsStomatognathic DiseasesAlcoholDental clearanceOral diseasesOral infectionsSmoking

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.