ArticleEuropean radiology2018
Bone susceptibility mapping with MRI is an alternative and reliable biomarker of osteoporosis in postmenopausal women.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- "One-stop-shop" medical imaging for osteoporosis and obese patients: a narrative review.Journal of endocrinological investigation · 2026Review
- Quantitative MRI methods for the assessment of structure, composition, and function of musculoskeletal tissues in basic research and preclinical applications.Magma (New York, N.Y.) · 2024Review
- Article
- Bone Biomarkers Based on Magnetic Resonance Imaging.Seminars in musculoskeletal radiology · 2024Review
- T2*-corrected Q-Dixon and reduced-FOV diffusion kurtosis imaging (DKI) parameters: correlation with QCT-derived bone mineral density (BMD) and ability to identify abnormal BMD and osteoporosis in postmenopausal women.Quantitative imaging in medicine and surgery · 2023Article
- Measuring Drug Therapy Effect on Osteoporotic Fracture Risk by Trabecular Bone Lacunarity: The LOTO Study.Biomedicines · 2023Article
- Quantifying calcium changes in the fetal spine using quantitative susceptibility mapping as extracted from STAGE imaging.European radiology · 2023Article
- Osteoporosis diagnosis in knee X-rays by transfer learning based on convolution neural network.Multimedia tools and applications · 2023Article
- Quantitative susceptibility mapping using multi-channel convolutional neural networks with dipole-adaptive multi-frequency inputs.Frontiers in neuroscience · 2023Article
- Simultaneous Quantitative Susceptibility Mapping of Articular Cartilage and Cortical Bone of Human Knee Joint Using Ultrashort Echo Time Sequences.Frontiers in endocrinology · 2022Article
- Survey of MRI Usefulness for the Clinical Assessment of Bone Microstructure.International journal of molecular sciences · 2021Review
- Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study.BMC musculoskeletal disorders · 2021Article
- Computer-aided diagnosis systems for osteoporosis detection: a comprehensive survey.Medical & biological engineering & computing · 2020Review
- Significant correlations between human cortical bone mineral density and quantitative susceptibility mapping (QSM) obtained with 3D Cones ultrashort echo time magnetic resonance imaging (UTE-MRI).Magnetic resonance imaging · 2019Article
- Reproducibility of quantitative susceptibility mapping in lumbar vertebra.Quantitative imaging in medicine and surgery · 2019Article
- Protective effect of resveratrol on estrogen deficiency-induced osteoporosis though attenuating NADPH oxidase 4/nuclear factor kappa B pathway by increasing miR-92b-3p expression.International journal of immunopathology and pharmacologyArticle
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6 authors.
Funding
Abstract
objectivesTo investigate the efficacy of quantitative susceptibility mapping (QSM) in the assessment of osteoporosis for postmenopausal women.
methodsBetween May and September 2017, a total of 70 postmenopausal women who underwent MRI-based QSM and quantitative computed tomography (QCT) were consecutively enrolled in this prospective study. The measurement of QSM and QCT values was performed on the L3 vertebrae body. On the basis of QCT value, all individuals were divided into three groups (normal, osteopenia and osteoporosis).
resultsOn the basis of QCT, 18 individuals were normal (25.7%), 26 osteopenic (37.1%) and 26 osteoporotic (37.1%). The QSM value was age-related (p = 0.04) and significantly higher in the osteoporosis group than in either the normal or osteopenia group (for all, p < 0.001). In addition, the QSM value was highly correlated with QCT value (r = - 0.720, p < 0.001). For QSM, the area under the curve (AUC), sensitivity and specificity for differentiating osteopenia from non-osteopenia were 0.88, 86.5% and 77.8%, respectively, and for differentiating osteoporosis from non-osteoporosis they were 0.86, 80.8% and 77.3%, respectively.
conclusionsMRI-based QSM could be used for quantifying susceptibility in vertebrae and has the potential to be a new biomarker in the assessment of osteoporosis for postmenopausal women. KEY POINTS: • Osteoporosis significantly increases risk of fracture for postmenopausal women. • QSM value was correlated with QCT value (r = - 0.72, p < 0.001). • QSM is feasible in the assessment of osteoporosis for postmenopausal women. • QSM offers the quantification of susceptibility within bone.
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