Evidence map›Paper›PMID 29948044›Full record

ReviewWorld journal of urology2019

Impact of multiparametric MRI and MRI-targeted biopsy on pre-therapeutic risk assessment in prostate cancer patients candidate for radical prostatectomy.

Paolo Dell'Oglio, Armando Stabile, Brendan Hermenigildo Dias, Giorgio Gandaglia, Elio Mazzone, Nicola Fossati, Vito Cucchiara, Emanuele Zaffuto, Vincenzo Mirone, Nazareno Suardi and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. All change in the prostate cancer diagnostic pathway.Nature reviews. Clinical oncology · 2020
    Review
  8. Review
  9. MRI-targeted biopsies: What's next?World journal of urology · 2019
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Paolo Dell'OglioDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Armando StabileDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Brendan Hermenigildo DiasDepartment of Urology, OLV Aalst, Aalst, Belgium.
Giorgio GandagliaDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Elio MazzoneDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Nicola FossatiDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Vito CucchiaraDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Emanuele ZaffutoDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Vincenzo MironeDepartment of Urology, Federico II University, Naples, Italy.
Nazareno SuardiDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Alexandre MottrieDepartment of Urology, OLV Aalst, Aalst, Belgium.
Francesco MontorsiDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy.
Alberto BrigantiDepartment of Urology and Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Urological Research Institute (URI), Via Olgettina 60, 20132, Milan, Italy. briganti.alberto@hsr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the current status and future potential of multiparametric MRI (mpMRI) and MRI-targeted biopsy (MRI-TBx) on the pretherapeutic risk assessment in prostate cancer patients' candidates for radical prostatectomy.

methodsA literature search of the MEDLINE/PubMed and Scopus database was performed. English-language original and review articles were analyzed and summarized after an interactive peer-review process of the panel.

resultsPretherapeutic risk assessment tools should be based on target plus systematic biopsies, where the addition of systematic biopsy (TRUS-Bx) to the mpMRI-target cores is associated with a lower rate of upgrading at final pathology. The combination of mpMRI findings with clinical parameters outperforms models based on clinical parameters alone in the prediction of adverse pathological outcomes and oncological results. This is particularly true when a specialized radiologist is present.

conclusionThe combination of mpMRI findings and clinical parameters should be considered to improve patient stratification in the pretherapeutic risk assessment. There is an urgent need to develop or include MRI data and MRI-TBx findings in available preoperative risk tools. This will allow improving the pretherapeutic risk assessment, providing important additional information for patient-tailored treatment planning and optimizing outcomes.

Indexed as

HumansImage-Guided BiopsyMagnetic Resonance ImagingMagnetic Resonance Imaging, InterventionalMaleProstateProstatectomyProstatic NeoplasmsRisk AssessmentMagnetic resonance imagingProstate cancerReviewRisk assessmentTargeted biopsy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.