ArticleRheumatology international2018
Lupus retinopathy: a marker of active systemic lupus erythematosus.
Article in Rheumatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 54 citations in OpenAlex.
- Article
- A deep learning system for detecting systemic lupus erythematosus from retinal images.Cell reports. Medicine · 2025Article
- Bilateral retinal vasculitis presenting as the first manifestation of systemic lupus erythematosus: a case report.Journal of medical case reports · 2025Article
- Choroidopathy in patients with systemic lupus erythematosus using enhanced depth imaging spectral domain optical coherence tomography and optical coherence tomography angiography.International journal of ophthalmology · 2025Article
- Retinal sublayer analysis in juvenile systemic lupus erythematosus without lupus retinopathy.Clinical rheumatology · 2024Article
- A case of choroidal neovascularization as a first manifestaion of systemic lupus erythematosus.International ophthalmology · 2024Article
- Ocular fundus changes and association with systemic conditions in systemic lupus erythematosus.Frontiers in immunology · 2024Review
- Quantitative assessment of retinal vasculature changes in systemic lupus erythematosus using wide-field OCTA and the correlation with disease activity.Frontiers in immunology · 2024Observational
- Bilateral Retinal Vasculitis as Initial Presentation of Systemic Lupus Erythematosus with Secondary Antiphospholipid Syndrome.The American journal of case reports · 2023Review
- Clinical Research of Lupus Retinopathy: Quantitative Analysis of Retinal Vessels by Optical Coherence Tomography Angiography in Patients with Systemic Lupus Erythematosus.Diagnostics (Basel, Switzerland) · 2023Article
- Relationship between retinal microvascular impairment and subclinical atherosclerosis in SLE.Lupus science & medicine · 2023Article
- Unilateral CRAO as the presenting clinical sign of systemic lupus erythematosus.American journal of ophthalmology case reports · 2023Article
- Rituximab, Intravitreal Bevacizumab and Laser Photocoagulation for Treatment of Macrophage Activation Syndrome and Retinal Vasculitis in Lupus: A Case Report.International journal of molecular sciences · 2023Article
- [Relationship between anti-ENO1 antibody and systemic lupus erythematosus patients with retinopathy].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- [Clinical and immunological characteristics of systemic lupus erythematosus with retinopathy].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- Evaluation of Subclinical Retinal Disease in Patients Affected by Systemic Lupus Erythematosus with No Evidence of Ocular Involvement-An Optical Coherence Tomography Angiography Original Study.Journal of clinical medicine · 2022Article
- Understanding Ocular Findings and Manifestations of Systemic Lupus Erythematosus: Update Review of the Literature.International journal of molecular sciences · 2022Review
- The full range of ophthalmological clinical manifestations in systemic lupus erythematosus.Frontiers in ophthalmology · 2022Article
- Retinopathy in newly-diagnosed systemic lupus erythematosus: should we screen for ocular involvement?BMC rheumatology · 2021Article
- Optical Coherence Tomography Angiography as a New Tool for Evaluation of the Subclinical Retinal Involvement in Patients with Systemic Lupus Erythematosus-A Review.Journal of clinical medicine · 2021Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retinopathy in the context of systemic lupus erythematosus (SLE) is associated with severe disease and poorer prognosis. We studied retinopathy in our cohort of Indian lupus patients. Four hundred and thirty-seven patients fulfilling the Systemic Lupus International Collaborating Clinics-American College of Rheumatology-2012 criteria, attending the department of Clinical Immunology were enrolled under this cross-sectional study. A comprehensive clinical (including ophthalmological) examination and immunological profile were performed. Retinopathy was defined if cotton-wool spots, haemorrhages, vasculitis, retinal detachment or optic disc changes as papilledema, optic atrophy were present. Disease activity was assessed using SLE disease activity index (SLEDAI). Mean age of participants was 28.06 ± 9.7 years (93.1% females); median disease duration 12 months (Interquartile range-IQR 6.36). Forty-five (10.3%) had SLE associated retinopathy. Autoimmune haemolytic anaemia [31.1 vs 14.5%, p value 0.004, odd's ratio-OR (95% confidence interval-CI) 2.65 (1.33-5.29)], serositis [33.3 vs 18.9%, p value 0.023, OR (CI) 2.14 (1.11-4.10)], lupus nephritis [62.2 vs 40.8%, p value 0.006, OR (CI) 2.38 (1.26-4.50)], seizures [28.9 vs 12.8%, p value 0.004, OR (CI) 2.77 (1.36-5.65)] and median SLEDAI score (24 vs 12, p < 0.01) were significantly higher in those with retinopathy. On adjusted binary logistic regression, autoimmune hemolytic anemia, lupus nephritis and presence of antibodies to Smith antigen were predictors for retinopathy. Retinopathy is common in SLE, a marker of active disease with frequent renal involvement and should be screened for in all patients with lupus.
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