ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2018
The genome of tapeworm Taenia multiceps sheds light on understanding parasitic mechanism and control of coenurosis disease.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Assembly of a high-quality reference genome for the rat tapewormbioRxiv : the preprint server for biology · 2026Article
- Chromosome-scale nuclear genome and proteome of Anoplocephala perfoliata elucidate lineage-specific features of a 'neglected' equine tapeworm.BMC genomics · 2026Article
- Discovery of new chromosomal markers through repeatome analysis of Caryophyllaeus laticeps (Caryophyllidea).Parasitology research · 2025Article
- Highly resolved genome assembly and comparative transcriptome profiling reveal genes related to developmental stages of tapewormProceedings. Biological sciences · 2024Article
- Phylogenomic Analysis of 155 Helminth Species Reveals Widespread Absence of Oxygen Metabolic Capacity.Genome biology and evolution · 2023Article
- Evolution of sexual systems, sex chromosomes and sex-linked gene transcription in flatworms and roundworms.Nature communications · 2022Article
- Cestodes in the genomic era.Parasitology research · 2022Review
- Taenia multiceps coenurosis: a review.Parasites & vectors · 2022Review
- Chromosome-scale Echinococcus granulosus (genotype G1) genome reveals the Eg95 gene family and conservation of the EG95-vaccine molecule.Communications biology · 2022Article
- The Genomes of Two Strains ofFrontiers in cellular and infection microbiology · 2022Article
- High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical regions.PLoS neglected tropical diseases · 2021Article
- The genome of the thin-necked bladder worm Taenia hydatigena reveals evolutionary strategies for helminth survival.Communications biology · 2021Article
- Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation.Communications biology · 2021Article
- Article
- Comparative Transcriptome Analyses of the Developmental Stages ofFrontiers in veterinary science · 2021Article
- Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm.Communications biology · 2020Article
- Article
- Evidence for densovirus integrations into tapeworm genomes.Parasites & vectors · 2019Article
- Coenurosis of Yak, Bos grunniens, caused by Taenia multiceps: A Case Report with Molecular Identification in Qinghai Tibetan Plateau Area, China.The Korean journal of parasitology · 2019Article
- Molecular characterisation and expression analysis of two heat-shock proteins in Taenia multiceps.Parasites & vectors · 2019Article
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Authors and funding
21 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coenurosis, caused by the larval coenurus of the tapeworm Taenia multiceps, is a fatal central nervous system disease in both sheep and humans. Though treatment and prevention options are available, the control of coenurosis still faces presents great challenges. Here, we present a high-quality genome sequence of T. multiceps in which 240 Mb (96%) of the genome has been successfully assembled using Pacbio single-molecule real-time (SMRT) and Hi-C data with a N50 length of 44.8 Mb. In total, 49.5 Mb (20.6%) repeat sequences and 13, 013 gene models were identified. We found that Taenia spp. have an expansion of transposable elements and recent small-scale gene duplications following the divergence of Taenia from Echinococcus, but not in Echinococcus genomes, and the genes underlying environmental adaptability and dosage effect tend to be over-retained in the T. multiceps genome. Moreover, we identified several genes encoding proteins involved in proglottid formation and interactions with the host central nervous system, which may contribute to the adaption of T. multiceps to its parasitic life style. Our study not only provides insights into the biology and evolution of T. multiceps, but also identifies a set of species-specific gene targets for developing novel treatment and control tools for coenurosis.
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