ArticleInternational journal of epidemiology2018
Placental weight and birthweight: the relations with number of daily cigarettes and smoking cessation in pregnancy. A population study.
Article in International journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Birth outcomes following intrauterine exposure to electronic nicotine delivery systems: a systematic review and meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Pooled it
- Prevalence of dual use of combustible tobacco and E-cigarettes among pregnant smokers: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Smoking during pregnancy and its effect on placental weight: a Mendelian randomization study.BMC pregnancy and childbirth · 2024Pooled it
- Association between active tobacco use during pregnancy and infant respiratory health: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Do smoking abstinence periods among pregnant smokers improve birth weight? A secondary analysis of a randomised, controlled trial.BMJ open · 2024Trial
- Healthcare professionals' experiences of supporting pregnant women with mental illness with their smoking behaviors: a qualitative study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Article
- Placental size and umbilical vein volume blood flow.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Exploring and Accounting for Genetically Driven Effect Heterogeneity in Mendelian Randomization.Genetic epidemiology · 2025Article
- Using nicotine replacement therapy for smoking reduction in pregnancy: a qualitative study of pregnant women in the UK who smoke.BMJ open · 2024Article
- Short inter-pregnancy interval and birthweight: a reappraisal based on a follow-up study of all women in Norway with two singleton deliveries during 1970-2019.European journal of epidemiology · 2024Article
- The Relationship Between Reported Daily Nicotine Dose from NRT and Daily Cigarette Consumption in Pregnant Women Who Smoke in an Observational Cohort Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Observational
- Linking Prenatal Environmental Exposures to Lifetime Health with Epigenome-Wide Association Studies: State-of-the-Science Review and Future Recommendations.Environmental health perspectives · 2023Review
- The effect of cigarette smoking on first-trimester crown-rump length.Australasian journal of ultrasound in medicine · 2023Article
- Active or passive maternal smoking increases the risk of low birth weight or preterm delivery: Benefits of cessation and tobacco control policies.Tobacco induced diseases · 2023Review
- Cigarette smoking during pregnancy and adverse perinatal outcomes: a cross-sectional study over 10 years.BMC public health · 2022Article
- Tobacco use prevalence and its determinate factor in Ethiopia- finding of the 2016 Ethiopian GATS.BMC public health · 2022Article
- Article
- Transcriptomics and Other Omics Approaches to Investigate Effects of Xenobiotics on the Placenta.Frontiers in cell and developmental biology · 2021Review
- No association between early maternal HbA1c and offspring birthweight among women without pre-existing diabetes in Greenland.International journal of circumpolar health · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Background: We studied associations of number of daily cigarettes in the first trimester with placental weight and birthweight in women who smoked throughout pregnancy, and in women who stopped smoking after the first trimester. Methods: We included all women with delivery of a singleton in Norway (n = 698 891) during 1999-2014, by using data from the Medical Birth Registry of Norway. We assessed dose-response associations by applying linear regression with restricted cubic splines. Results: In total, 12.6% smoked daily in the first trimester, and 3.7% stopped daily smoking. In women who smoked throughout pregnancy, placental weight and birthweight decreased by number of cigarettes; however, above 11-12 cigarettes we estimated no further decrease (Pnon-linearity < 0.001). Maximum decrease in placental weight in smokers compared with non-smokers was 18.2 g [95% confidence interval (CI): 16.6 to 19.7], and for birthweight the maximum decrease was 261.9 g (95% CI: 256.1 to 267.7). In women who stopped smoking, placental weight was higher than in non-smokers and increased by number of cigarettes to a maximum of 16.2 g (95% CI: 9.9 to 22.6). Birthweight was similar in women who stopped smoking and non-smokers, and we found no change by number of cigarettes (Pnon-linearity < 0.001). Conclusions: In women who smoked throughout pregnancy, placental weight and birthweight decreased non-linearly by number of cigarettes in the first trimester. In women who stopped smoking, placental weight was higher than in non-smokers and increased linearly by number of cigarettes; birthweight was almost similar to that of non-smokers.
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