Evidence map›Paper›PMID 29947730›Full record

ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2018

Sex Differences in the Association between Heavy Drinking and Behavioral Distress Tolerance and Emotional Reactivity Among Non-Depressed College Students.

Paola Pedrelli, Laura MacPherson, Amanda J Khan, Benjamin G Shapero, Lauren B Fisher, Maren Nyer, Paolo Cassano, Lindsey Parnarouskis, Amy Farabaugh, Maurizio Fava and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  5. Prelimbic Cortex Activity during a Distress Tolerance Task Predicts Cocaine-Seeking Behavior in Male, But Not Female Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Paola PedrelliDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Laura MacPhersonGreenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, USA.
Amanda J KhanEmotion and Learning Lab, Department of Psychology, Suffolk University, Boston, MA, USA.
Benjamin G ShaperoDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Lauren B FisherDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Maren NyerDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Paolo CassanoDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Lindsey ParnarouskisDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Amy FarabaughDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Maurizio FavaDepartment of Psychiatry, Depression Clinical Research Program, Massachusetts General Hospital, Boston, MA, USA.
Marisa M SilveriDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Harvard University · USMassachusetts General Hospital · USSuffolk University · USUniversity of Maryland, Baltimore · US

Funding

Mentoring in Patient-Oriented Neuroscience ResearchK24AA025977 · NIAAA · MCLEAN HOSPITAL · PI MARISA M SILVERI · 2017 to 2026
$1.6M
NIAAA NIH HHS K24 AA025977
6 · The paper itself

Abstract

backgroundHeavy episodic drinking (HED) is a common behavior among college students that is associated with severe negative consequences. Negative reinforcement processes have been applied to elucidate mechanisms underlying relationships between consumption of alcohol and the desire to alleviate negative feelings. Distress tolerance (DT) and emotional reactivity are two mechanisms that are consistent with the self-medication model that may contribute to HED. The current study investigated relationships between DT, emotional reactivity, defined as frustration reactivity and irritability reactivity, and HED in a non-depressed college population. Given differential patterns of consumption and motivation for drinking between males and females, sex differences were also examined. SHORT SUMMARY: The study examined two constructs consistent with negative reinforcement processes, behavioral distress tolerance (DT) and emotional reactivity (frustration reactivity and irritability reactivity), to explain heavy episodic drinking (HED) among non-depressed college students. Behavioral DT and frustration reactivity independently predicted HED. Higher HED was associated with higher frustration reactivity and lower behavioral DT in women, but nor in men.

methodsOne-hundred-ten college students without depressive symptoms completed alcohol use measures and the Paced Auditory Serial Attention Task (PASAT-C) to assess behavioral DT and emotional reactivity.

resultsDT and frustration reactivity independently predicted HED. The association between DT and HED was moderated by sex such that higher levels of DT predicted higher HED among females, but not among males. Higher frustration reactivity scores were associated with a greater number of HED.

conclusionsResults provide supporting evidence that DT and emotional reactivity are distinct factors, and that they predict HED independently. Results underscore the importance of examining sex differences when evaluating the association between HED and negative reinforcement processes in this population.

Indexed as

Sex CharacteristicsUniversitiesAdolescentAlcohol Drinking in CollegeCross-Sectional StudiesDepressionEmotionsFemaleHumansMaleStudentsYoung Adult

Identifiers

PMID29947730
PMCPMC6454502
OpenAlexW2810891677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.