Evidence map›Paper›PMID 29947685›Full record

ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2018

SALIVARY CORTISOL AND METABOLIC SYNDROME COMPONENT'S ASSOCIATION.

Grasiane Izidorio Garbellotto, Fernanda Jardim Reis, Ana Maria Pandolfo Feoli, Carla Haas Piovesan, Andréia da Silva Gustavo, Margareth da Silva Oliveira, Fabrício Edler Macagnan, Carlos Alexandre Sanchez Ferreira, Moisés Evandro Bauer, Cácio Ricardo Wietzycoski

Abstract read
In one paragraph

Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. ALVEOLAR BONE PATTERN AND SALIVARY LEPTIN LEVELS AMONG PREMENOPAUSAL OBESE WOMEN.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grasiane Izidorio GarbellottoFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Fernanda Jardim ReisFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Ana Maria Pandolfo FeoliFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Carla Haas PiovesanFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Andréia da Silva GustavoFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Margareth da Silva OliveiraFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Fabrício Edler MacagnanFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.
Carlos Alexandre Sanchez FerreiraPost-graduate Programa in Molecular and Cellular Biology, Biosciences Faculty, PUCRS, Porto Alegre, RS, Brazil.
Moisés Evandro BauerPost-graduate Programa in Molecular and Cellular Biology, Biosciences Faculty, PUCRS, Porto Alegre, RS, Brazil.
Cácio Ricardo WietzycoskiFaculty of Nursing, Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundActually the lifestyle exposes the population to several risk factors related to alimentary habits and less physical activity that contributes to chronic diseases appearance worldwide.

aimTo analyze the association between salivary cortisol and the components of metabolic syndrome.

methodsThis is a cross-sectional study. As part of it, 28 individuals aged 30-59 years presenting three or more of the following findings: CA: ≥88 cm for women and ≥102 cm for men; SBP>130 mmHg and DBP>85 mmHg; GL>100 mg/dl; TG>150 mg/dl; HDL<40 mg/dl for men and <50 mg/dl for women. Was performed analysis of salivary cortisol (by radioimmunoassay) from 25 salivary samples collected throughout the day, for evaluating changes in the circadian rhythm of this hormone (8AM, noon and 8PM).

results28 evaluated individuals had a mean age of 51.9±7.5 years, mostly women (64.3%) and a mean of BMI 33.6±3.2 kg/m². The cortisol level from the 8AM averaged 18.7±4.8 ng/dlL. Individuals with FPG>110mg/dl, have significantly lower average levels of cortisol than ones with FPG <110 (12.8±5,2 vs. 17.3±4.2). Significant correlations were HOMA vs. WC (r=0,465; p˂0,005) and TG (r=0,473; p˂0,005), WC vs. FG (r=0,446; p˂0,005) and BMI (r=0,730; p˂0.0001); TG vs. HDL (r=0,441 p˂0,005) and FG (r=0,440; p˂0,005).

conclusionMorning salivary cortisol in subjects with chronically elevated blood glucose can represent a downregulation of the hypothalamic-pituitary adrenal axis. This is an important finding not yet well investigated.

Indexed as

AdultCross-Sectional StudiesFemaleHumansHydrocortisoneMaleMetabolic SyndromeMiddle AgedSalivaHydrocortisone

Identifiers

PMID29947685
PMCPMC6049990

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.