ArticleJournal of psychiatry & neuroscience : JPN2018
Examining cognition across the bipolar/schizophrenia diagnostic spectrum.
Article in Journal of psychiatry & neuroscience : JPN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Outcomes and clinical implications of intranasal insulin on cognition in humans: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Videogame training increases clinical well-being, attention and hippocampal-prefrontal functional connectivity in patients with schizophrenia.Translational psychiatry · 2024Trial
- Rethinking schizophrenia: insights from genomics and implications for research.Molecular psychiatry · 2026Review
- Restoring Synaptic Balance in Schizophrenia: Insights From a Thalamo-Cortical Conductance-Based Model.Schizophrenia bulletin · 2026Article
- Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study.Acta psychiatrica Scandinavica · 2026Article
- Attenuated theta-band activity and cross-frequency coupling in schizophrenia during affective response inhibition.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Effects of Shared and Nonshared Schizophrenia and Bipolar Disorder Alleles on Cognition and Educational Attainment in the UK Biobank.Biological psychiatry global open science · 2025Article
- Relationships between cognition and symptoms across mood and psychotic disorders.Psychiatry research · 2025Article
- Peak Alpha Frequency in Schizophrenia, Bipolar Disorder, and Healthy Volunteers: Associations With Visual Information Processing and Cognition.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- The Association Between Prolactin Levels and Cognitive Function in Female Patients With Severe Mental Disorders.Psychiatry investigation · 2024Article
- Processing speed mediates the relationship between DDR1 and psychosocial functioning in euthymic patients with bipolar disorder presenting psychotic symptoms.Molecular psychiatry · 2024Article
- Cardiff Online Cognitive Assessment in a National Sample: Cross-Sectional Web-Based Study.Journal of medical Internet research · 2023Article
- DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts.BJPsych open · 2023Article
- Cognitive insight and introspective accuracy in individuals with bipolar disorder: A scoping review.Neuroscience applied · 2023Review
- Validity of remote administration of the MATRICS Consensus Cognitive Battery for individuals with severe mental illness.Schizophrenia research. Cognition · 2022Article
- Web-Based Cognitive Testing in Psychiatric Research: Validation and Usability Study.Journal of medical Internet research · 2022Article
- Lack of Support for the Genes by Early Environment Interaction Hypothesis in the Pathogenesis of Schizophrenia.Schizophrenia bulletin · 2022Article
- Cortical and Subcortical Structural Morphometric Profiles in Individuals with Nonaffective and Affective Early Illness Psychosis.Schizophrenia bulletin open · 2022Article
- Cortical activation abnormalities in bipolar and schizophrenia patients in a combined oddball-incongruence paradigm.European archives of psychiatry and clinical neuroscience · 2021Article
- A genome-wide association study of the longitudinal course of executive functions.Translational psychiatry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundCognitive impairments are well-established features of schizophrenia, but there is ongoing debate about the nature and degree of cognitive impairment in patients with schizoaffective disorder and bipolar disorder. We hypothesized that there is a spectrum of increasing impairment from bipolar disorder to schizoaffective disorder bipolar type, to schizoaffective disorder depressive type and schizophrenia.
methodsWe compared performance on the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery between participants with schizophrenia (
resultsCognitive impairments increased in severity from bipolar disorder to schizoaffective disorder bipolar type, to schizophrenia and schizoaffective disorder depressive type. Participants with schizophrenia and schizoaffective disorder depressive type showed equivalent performance ( LIMITATIONS: There were fewer participants with schizoaffective disorder and bipolar disorder than schizophrenia. Despite this, our analyses were robust to differences in group sizes, and we were able to detect differences between groups.
conclusionCognitive impairments represent a symptom dimension that cuts across traditional diagnostic boundaries.
Indexed as
Identifiers
29947606PMC6019354What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.