ArticlePlant biotechnology journal2019
Genetic architecture underlying the lignin biosynthesis pathway involves noncoding RNAs and transcription factors for growth and wood properties in Populus.
Article in Plant biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 89 citations in OpenAlex.
- Identification and Characterization of Genes Associated With Wood Property Traits via Genome Sequencing in Fast-Growing Species of GenusEvolutionary applications · 2026Article
- Deciphering the Biosynthetic Pathways and Regulatory Networks of the Active Components ofInternational journal of molecular sciences · 2026Article
- Advances of Long Non-Coding RNA in Perennial Plants: Development and Stress Responses.Plants (Basel, Switzerland) · 2025Review
- Integrative analyses reveal Bna-miR397a-BnaLAC2 as a potential modulator of low-temperature adaptability in Brassica napus L.Plant biotechnology journal · 2025Article
- Insights into Molecular Mechanism of Secondary Xylem Rapid Growth inPlants (Basel, Switzerland) · 2025Article
- A transcription factor, PbWRKY24, contributes to russet skin formation in pear fruits by modulating lignin accumulation.Horticulture research · 2025Article
- Genome-wide characterization of post-transcriptional processes related to wood formation in Dalbergia odorifera.BMC genomics · 2024Article
- Integrating ATAC-seq and RNA-seq to identify differentially expressed genes with chromatin-accessible changes during photosynthetic establishment in Populus leaves.Plant molecular biology · 2023Article
- Effect of T-DNA Integration on Growth of TransgenicInternational journal of molecular sciences · 2023Article
- Genome-wide identification of auxin-responsive microRNAs in the poplar stem.Genes & genomics · 2023Article
- MdERF114 enhances the resistance of apple roots to Fusarium solani by regulating the transcription of MdPRX63.Plant physiology · 2023Article
- Growth-regulating factor 15-mediated gene regulatory network enhances salt tolerance in poplar.Plant physiology · 2023Article
- Enhanced genome-wide association reveals the role of YABBY11-NGATHA-LIKE1 in leaf serration development of Populus.Plant physiology · 2023Article
- Article
- Multiomics studies with co-transformation reveal microRNAs via miRNA-TF-mRNA network participating in wood formation inFrontiers in plant science · 2023Article
- Lignin and Its Pathway-Associated Phytoalexins Modulate Plant Defense against Fungi.Journal of fungi (Basel, Switzerland) · 2022Review
- Construction of two regulatory networks related to salt stress and lignocellulosic synthesis under salt stress based on a Populus davidiana × P. bolleana transcriptome analysis.Plant molecular biology · 2022Article
- Integrated SMRT and Illumina Sequencing Provide New Insights into Crocin Biosynthesis ofInternational journal of molecular sciences · 2022Article
- The genome of oil-Camellia and population genomics analysis provide insights into seed oil domestication.Genome biology · 2022Article
- Transcriptome and association mapping revealed functional genes respond to drought stress inFrontiers in plant science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Lignin provides structural support in perennial woody plants and is a complex phenolic polymer derived from phenylpropanoid pathway. Lignin biosynthesis is regulated by coordinated networks involving transcription factors (TFs), microRNAs (miRNAs) and long noncoding RNAs (lncRNAs). However, the genetic networks underlying the lignin biosynthesis pathway for tree growth and wood properties remain unknown. Here, we used association genetics (additive, dominant and epistasis) and expression quantitative trait nucleotide (eQTN) mapping to decipher the genetic networks for tree growth and wood properties in 435 unrelated individuals of Populus tomentosa. We detected 124 significant associations (P ≤ 6.89E-05) for 10 growth and wood property traits using 30 265 single nucleotide polymorphisms from 203 lignin biosynthetic genes, 81 TF genes, 36 miRNA genes and 71 lncRNA loci, implying their common roles in wood formation. Epistasis analysis uncovered 745 significant pairwise interactions, which helped to construct proposed genetic networks of lignin biosynthesis pathway and found that these regulators might affect phenotypes by linking two lignin biosynthetic genes. eQTNs were used to interpret how causal genes contributed to phenotypes. Lastly, we investigated the possible functions of the genes encoding 4-coumarate: CoA ligase and cinnamate-4-hydroxylase in wood traits using epistasis, eQTN mapping and enzymatic activity assays. Our study provides new insights into the lignin biosynthesis pathway in poplar and enables the novel genetic factors as biomarkers for facilitating genetic improvement of trees.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.