Evidence map›Paper›PMID 29947353›Full record

ArticleOncology nursing forum2018

Clinical Characteristics of Children and Adolescents Undergoing Hematopoietic Cell Transplantation Who Develop Oral Mucositis.

Clare Donohoe, Judy K Bosi, April Sykes, Zhaohua Lu, Belinda Mandrell

Open access · greenAbstract read
In one paragraph

Article in Oncology nursing forum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Chemotherapy-induced oral mucositis: hierarchical analysis of recurrence factors.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
  4. Incidence, severity, and temporal development of oral complications in pediatric allogeneic hematopoietic stem cell transplant patients - a multicenter study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clare DonohoeUniversity of Michigan.
Judy K BosiSt. Jude Children's Research Hospital.
April SykesSt. Jude Children's Research Hospital.
Zhaohua Lu
Belinda MandrellSt. Jude Children's Research Hospital.
St. Jude Children's Research Hospital · USUniversity of Michigan–Ann Arbor · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
PROFESSIONAL ONCOLOGY EDUCATION PROGRAMR25CA023944 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SUZANNE A. GRONEMEYER · 1986 to 2026
$8.3M
Complexity: Innovations in Promoting Health through Team ScienceT32NR016914 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARJORIE E MCCULLAGH · 2017 to 2026
$3.5M
NCI NIH HHS P30 CA021765NCI NIH HHS R25 CA023944NINR NIH HHS T32 NR016914
6 · The paper itself

Abstract

objectivesTo describe the clinical characteristics of children and adolescents undergoing hematopoietic cell transplantation (HCT) who develop oral mucositis. SAMPLE &

setting45 patients who underwent HCT from July 2015 to May 2016 at St. Jude Children's Research Hospital in Memphis, Tennessee. METHODS & VARIABLES: Clinical factors were described as transplantation type, mucositis severity or grade, mucositis duration, days to engraftment, total parenteral nutrition (TPN) support, IV opioid pain management use during mucositis, positive blood or oral cultures, and length of hospitalization, then compared across mucositis grade.

results24 patients had grade 3 or greater mucositis onset from day -3 to day 9 of transplantation; of these, 23 required IV opioid medication to treat mucosal pain. Patients with mucositis grade 3 or greater were more likely to have undergone an allogeneic transplantation, receive TPN, have documented positive blood or oral cultures, and have longer hospitalizations than those with low-grade mucositis. IMPLICATIONS FOR NURSING: Nurses are in a unique position to propose and administer interventions to prevent and alleviate symptoms of mucositis.

Indexed as

AdolescentAdultAnalgesics, OpioidChildChild, PreschoolFemaleHematopoietic Stem Cell TransplantationHumansMalePainPain ManagementStomatitisTennesseeTransplantation, HomologousYoung AdultAnalgesics, Opioidchildren and adolescentshematopoietic cell transplantationoral mucositis

Identifiers

PMID29947353
PMCPMC6152915
OpenAlexW2810186458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.