ArticleEndocrinology and metabolism (Seoul, Korea)2018
Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study.
Article in Endocrinology and metabolism (Seoul, Korea), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The Association of Overt and Subclinical Hyperthyroidism with the Risk of Cardiovascular Events and Cardiovascular Mortality: Meta-Analysis and Systematic Review of Cohort Studies.Endocrinology and metabolism (Seoul, Korea) · 2020Pooled it
- The impact of the media coverage on the thyroid cancer overdiagnosis issue concerning the surgical trends in South Korea, 2012-2017: a retrospective multicenter cohort study.Annals of surgical treatment and research · 2026Article
- Thyroid dysfunction and its associated factors: a cross-sectional study based on Rafsanjan cohort study in the southeast of Iran.BMJ open · 2026Article
- Association between Benign Thyroid Disorders and Breast Cancer Risk in Korean Women.Cancer research and treatment · 2026Article
- New Onset of Hair Loss Disorders During the Coronavirus Disease 2019 Pandemic: A Korean Nationwide Population-Based Study.Annals of dermatology · 2025Article
- Incidence and Risk Factors for Amiodarone-Induced Thyroid Dysfunction: A Nationwide Retrospective Cohort Study.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025Article
- Rising Incidence and Comorbidities of Endogenous Hypothyroidism in Republic of Korea from 2004 to 2018: A Nationwide Population Study.Endocrinology and metabolism (Seoul, Korea) · 2024Article
- Article
- Epidemiology of Carpal Tunnel Syndrome and Trigger Finger in South Korea: A Nationwide Population-Based Study.Clinics in orthopedic surgery · 2024Article
- Myotonic dystrophy type 1 in South Korea: a comprehensive analysis of cancer and comorbidity risks.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Increased risk of incident gout in patients with hyperthyroidism: a nationwide retrospective cohort study.Rheumatology international · 2024Article
- The relationship between dietary total flavonoids and thyroid function in U.S.adults, NHANES 2007-2010.PloS one · 2024Article
- Comprehensive analysis of chemokine gene polymorphisms in Korean children with autoimmune thyroid disease.Scientific reports · 2023Article
- Acromegaly and the long-term fracture risk of the vertebra and hip: a national cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- The Current Status of Hyperthyroidism in Korea.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Prevalence, Treatment Status, and Comorbidities of Hyperthyroidism in Korea from 2003 to 2018: A Nationwide Population Study.Endocrinology and metabolism (Seoul, Korea) · 2023Observational
- Preoperative Risk Stratification of Follicular-patterned Thyroid Lesions on Core Needle Biopsy by Histologic Subtyping and RAS Variant-specific Immunohistochemistry.Endocrine pathology · 2023Article
- Association of ITM2A rs1751094 polymorphism on X chromosome in Korean pediatric patients with autoimmune thyroid disease.Immunity, inflammation and disease · 2023Article
- Cancer and Mortality Risks of Graves' Disease in South Korea Based on National Data from 2010 to 2019.Clinical epidemiology · 2023Article
- Graves' Disease and the Risk of End-Stage Renal Disease: A Korean Population-Based Study.Endocrinology and metabolism (Seoul, Korea) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of thyroid nodules has increased worldwide in recent years. Thyroid dysfunction is a potential risk factor for hypercholesterolemia, cardiovascular disease, osteoporosis, arrhythmia, and neuropsychiatric disease. This study investigated the prevalence and annual incidence of thyroid nodules, hypothyroidism, and hyperthyroidism in Koreans.
methodsIn this nationwide population-based cohort study, 51,834,660 subjects were included using the National Health Information database from 2006 to 2015, after the exclusion of subjects with thyroid cancer.
resultsThe prevalence in Korea in 2015 of thyroid nodules, hypothyroidism in patients taking thyroid hormone, and hyperthyroidism in patients undergoing treatment was 15.82/1,000 population, 15.94/1,000 population, and 2.76/1,000 population, respectively. All these diseases were more prevalent among women than among men. The number of incident cases of these three thyroid diseases steadily increased from 2006 to 2012, and then decreased through 2015. The incidence of thyroid nodules, hypothyroidism treated with thyroid hormone, and treated hyperthyroidism was 6.79/1,000 population, 1.76/1,000 population, and 0.55/1,000 population, respectively, in Korea in 2015. The use of methimazole continuously increased, from 33% of total antithyroid drug prescriptions in 2006 to 74.4% in 2015, and it became the most frequently prescribed antithyroid drug in Korea. In contrast, the use of propylthiouracil continuously decreased.
conclusionThis was the first nationwide study of the prevalence and annual incidence of thyroid nodules, hypothyroidism, and hyperthyroidism to take into account recent changes and to include the current status of patients receiving treatment.
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