ArticleHuman brain mapping2018
Exploring 3-hinge gyral folding patterns among HCP Q3 868 human subjects.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- DEEP-GYRALNET: ENABLING MACHINE LEARNING IN GYRAL FOLDING PATTERN EXTRACTION ON CORTICAL SURFACE.Proceedings. IEEE International Symposium on Biomedical Imaging · 2026Article
- Mechanics of the Spatiotemporal Evolution of Sulcal Pits in the Folding Brain.Human brain mapping · 2025Article
- USING STRUCTURAL SIMILARITY AND KOLMOGOROV-ARNOLD NETWORKS FOR ANATOMICAL EMBEDDING OF CORTICAL FOLDING PATTERNS.Proceedings. IEEE International Symposium on Biomedical Imaging · 2025Article
- UNSUPERVISED CORTICAL SURFACE REGISTRATION NETWORK FOR ALIGNING GYRALNET.Proceedings. IEEE International Symposium on Biomedical Imaging · 2025Article
- Article
- MILD COGNITIVE IMPAIRMENT CLASSIFICATION USING A NOVEL FINER-SCALE BRAIN CONNECTOME.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024Article
- ENHANCING GROUP-WISE CONSISTENCY IN 3-HINGE GYRUS MATCHING VIA ANATOMICAL EMBEDDING AND STRUCTURAL CONNECTIVITY OPTIMIZATION.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024Article
- Mechanical hierarchy in the formation and modulation of cortical folding patterns.Scientific reports · 2023Article
- An integrated finite element method and machine learning algorithm for brain morphology prediction.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Identification for the cortical 3-Hinges folding pattern based on cortical morphological and structural features.Frontiers in neuroscience · 2023Article
- Cortical thickness systematically varies with curvature and depth in healthy human brains.Human brain mapping · 2022Article
- Cortical development coupling between surface area and sulcal depth on macaque brains.Brain structure & function · 2022Article
- Mechanism Exploration of 3-Hinge Gyral Formation and Pattern Recognition.Cerebral cortex communications · 2021Article
- Cortical 3-hinges could serve as hubs in cortico-cortical connective network.Brain imaging and behavior · 2020Article
- Identifying Cross-individual Correspondences of 3-hinge Gyri.Medical image analysis · 2020Article
- Exploring 3-hinge gyral folding patterns among HCP Q3 868 human subjects.Human brain mapping · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
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Abstract
Comparison and integration of neuroimaging data from different brains and populations are fundamental in neuroscience. Over the past decades, the neuroimaging field has largely depended on image registration to compare and integrate neuroimaging data from individuals in a common reference space, with a basic assumption that the brains are similar. However, the intrinsic neuroanatomical complexity and huge interindividual cortical folding variation remain underexplored. Here we focus on a specific cortical convolution pattern, termed 3-hinge gyral folding, which is the conjunction of gyri from multiple orientations and has unique and consistent anatomically, structurally, and functionally connective patterns across subjects. By developing a novel shape descriptor and a two-stage clustering pipeline, we devise an automatic method to identify 3-hinges in the Human Connectome Project Q3 868 human brains, and further parameterize the complexity of such a pattern and quantify its regularity and variation in terms of 3-hinge number, position, and morphology. Our results not only exhibit the huge interindividual variations, but also reveal regular relationship between gyral hinges and other factors, such as their locations and cortical morphologies. It is found that "line-shape" cortices have relatively more consistent 3-hinge shape pattern distributions, and certain types of 3-hinge patterns favor particular cortical morphologies. In addition, more 3-hinges are found on "line-shape" cortices while their numbers vary more across subjects than those on "non-line-shape" cortices. This study adds new insights into a better understanding of the regularity and variability of human brain anatomy, and their functional aspects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.