Evidence map›Paper›PMID 29946560›Full record

ArticleInternational journal of cardiology. Heart & vasculature2018

Effect of cardiac rehabilitation on the renal function in chronic kidney disease - Analysis using serum cystatin-C based glomerular filtration rate.

Tomoaki Hama, Keiko Oikawa, Akiko Ushijima, Norishige Morita, Takashi Matsukage, Yu-Ji Ikari, Yoshinori Kobayashi

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Effect of Cardiac Rehabilitation on Cardiovascular Events in Patients With Advanced Chronic Kidney Disease.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025
    Article
  3. Article
  4. Observational
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Cardiac rehabilitation services: A global perspective on performance and barriers.International journal of cardiology. Heart & vasculature · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tomoaki HamaThe Department of Internal Medicine, Division of Cardiology, Tokai University Hachioji-Hospital, Japan.
Keiko OikawaThe Department of Internal Medicine, Division of Cardiology, Tokai University Hachioji-Hospital, Japan.
Akiko UshijimaThe Department of Internal Medicine, Division of Cardiology, Tokai University Hachioji-Hospital, Japan.
Norishige MoritaThe Department of Internal Medicine, Division of Cardiology, Tokai University Hachioji-Hospital, Japan.
Takashi MatsukageThe Department of Internal Medicine, Division of Cardiology, Tokai University Hachioji-Hospital, Japan.
Yu-Ji IkariThe Department of Internal Medicine, Division of Cardiology, Tokai University Hospital, Japan.
Yoshinori KobayashiThe Department of Internal Medicine, Division of Cardiology, Tokai University Hachioji-Hospital, Japan.
Tokai University Hachioji Hospital · JPTokai University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether an individually determined appropriate level of cardiac rehabilitation (CR) has a favorable effect on the renal function still remains unclarified. The aim of this study was to confirm the effect of CR on the estimated glomerular filtration rate (eGFR) using cystatin C, which is known to be unaffected by physical exercise.

methodsThe study population was comprised of 86 patients (61 males; average age 74 y/o) with a lower-moderate level of chronic kidney disease (CKD) who was admitted to our hospital for treatment of cardiovascular disease (CVD) and who participated in our 3-month CR program. The exercise capacity was assessed by cardiopulmonary exercise testing (CPX) and the eGFR was measured by a formula based on the serum cystatin C concentration (eGFRcys) in each patient both at the beginning and end of the CR.

resultsIn the CVD patients with CKD, both the peak oxygen uptake (VO

conclusionsIn CVD patients, a novel CR program significantly improved the exercise capacity. Further, CR was shown to have a favorable effect on the renal function when it was estimated by the eGFRcys.

Indexed as

Cardiac rehabilitationCardiovascular diseaseChronic kidney diseaseCystatin CEstimated glomerular filtration rateExercise capacity

Identifiers

PMID29946560
PMCPMC6016066
OpenAlexW2801729356

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.