ArticleDiabetology & metabolic syndrome2018
Optimal cut-off points for waist circumference in the definition of metabolic syndrome in Brazilian adults: baseline analyses of the Longitudinal Study of Adult Health (ELSA-Brasil).
Article in Diabetology & metabolic syndrome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Cardiovascular risk factors among adult patients with haemophilia.International journal of hematology · 2021Trial
- Prevalence of obesity according to body mass index, waist circumference, and waist-to-height ratio in Peru: A systematic review and meta-analysis.Obesity pillars · 2025Article
- Exploring the interplay between emotional attitudes towards diabetes, eating behaviour and glycaemic control in patients with type 2 diabetes mellitus.Public health nutrition · 2024Observational
- Body Mass Index and Waist Circumference as Predictors of Above-Average Increased Cardiovascular Risk Assessed by the SCORE2 and SCORE2-OP Calculators and the Proposition of New Optimal Cut-Off Values: Cross-Sectional Single-Center Study.Journal of clinical medicine · 2024Article
- Probiotic supplementation for 24 weeks in patients with non-alcoholic steatohepatitis: the PROBILIVER randomized clinical trial.Frontiers in nutrition · 2024Article
- Patterns of metabolic syndrome and associated factors in women from the ELSA-Brasil: a latent class analysis approach.Cadernos de saude publica · 2023Article
- Waist circumference cut-off points to identify major cardiovascular events and incident diabetes in Latin America: findings from the prospective Urban rural epidemiology study Colombia.Frontiers in cardiovascular medicine · 2023Article
- Metabolic syndrome and its association with changes in modifiable risk factors: Epifloripa aging study.Journal of diabetes and metabolic disorders · 2022Article
- Common BMI and diabetes-related genetic variants: A pilot study among indigenous people in the Brazilian Amazon.Genetics and molecular biology · 2022Article
- Optimal waist circumference cutoff values to predict cardiometabolic alterations in a Venezuela national representative sample. The EVESCAM study.Archivos de cardiologia de Mexico · 2020Article
- Optimal cut-off points for waist circumference in the definition of metabolic syndrome in Chile.Public health nutrition · 2020Article
- Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome.Pediatric gastroenterology, hepatology & nutrition · 2020Review
- Neutrophil-Lymphocyte Ratio in Patients with Acute Heart Failure Predicts In-Hospital and Long-Term Mortality.Journal of clinical medicine · 2020Article
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Abstract
backgroundWaist circumference (WC) has been incorporated in the definition of the metabolic syndrome (MetS) but the exact WC cut-off points across populations are not clear. The Joint Interim Statement (JIS) suggested possible cut-offs to different populations and ethnic groups. However, the adequacy of these cut-offs to Brazilian adults has been scarcely investigated. The objective of the study is to evaluate possible WC thresholds to be used in the definition of MetS using data from the Longitudinal Study of Adult Health (ELSA-Brasil), a multicenter cohort study of civil servants (35-74 years old) of six Brazilian cities.
methodsWe analyzed baseline data from 14,893 participants (6772 men and 8121 women). A MetS was defined according to the JIS criteria, but excluding WC and thus requiring 2 of the 4 remaining elements. We used restricted cubic spline regression to graph the relationship between WC and MetS. We identified optimal cut-off points which maximized joint sensitivity and specificity (Youden's index) from Receiver Operator Characteristic Curves. We also estimated the C-statistics using logistic regression.
resultsWe found no apparent threshold for WC in restricted cubic spline plots. Optimal cut-off for men was 92 cm (2 cm lower than that recommended by JIS for Caucasian/Europids or Sub-Saharan African men), but 2 cm higher than that recommended for ethnic Central and South American. For women, optimal cut-off was 86, 6 cm higher than that recommended for Caucasian/Europids and ethnic Central and South American. Optimal cut-offs did not very across age groups and most common race/color categories (except for Asian men, 87 cm).
conclusionsSex-specific cut-offs for WC recommended by JIS differ from optimal cut-offs we found for adult men and women of Brazil´s most common ethnic groups.
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