ArticleChinese medicine2018
Isorhynchophylline alleviates learning and memory impairments induced by aluminum chloride in mice.
Article in Chinese medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Dual protective role of curcumin- encapsulated chitosan nanoparticles against gastric and neural injury in a rat model of gut-brain axis dysfunction: a histological and biochemical study.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- A Systematic Review of Preclinical Studies Investigating the Effects of Pharmacological Agents on Learning and Memory in Prolonged Aluminum-Exposure-Induced Neurotoxicity.Brain sciences · 2025Review
- Zinc Oxide Nanoparticles Attenuated Neurochemical and Histopathological Alterations Associated with Aluminium Chloride Intoxication in Rats.Biological trace element research · 2025Article
- Rosiridin Protects Against Aluminum Chloride-Induced Memory Impairment via Modulation of BDNF/NFκB/PI3K/Akt Pathway in Rats.Medicina (Kaunas, Lithuania) · 2024Article
- Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases.Signal transduction and targeted therapy · 2023Review
- The activation of spliced X-box binding protein 1 by isorhynchophylline therapy improves diabetic encephalopathy.Cell biology and toxicology · 2023Article
- Isorhynchophylline alleviates cartilage degeneration in osteoarthritis by activating autophagy of chondrocytes.Journal of orthopaedic surgery and research · 2023Article
- Protective effect of hot peppers against amyloid β peptide and brain injury in AlClIranian journal of basic medical sciences · 2023Article
- Isorhynchophylline ameliorates stress-induced emotional disorder and cognitive impairment with modulation of NMDA receptors.Frontiers in neuroscience · 2022Article
- Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration byIranian journal of basic medical sciences · 2021Article
- The Potentials of Uncariae Ramulus Cum Uncis for the Treatment of Migraine: Targeting CGRP in the Trigeminovascular System.Current neuropharmacology · 2021Review
- Iron Dyshomeostasis Participated in Rat Hippocampus Toxicity Caused by Aluminum Chloride.Biological trace element research · 2020Article
- Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice.Psychopharmacology · 2020Article
- Isorhynchophylline enhances Nrf2 and inhibits MAPK pathway in cardiac hypertrophy.Naunyn-Schmiedeberg's archives of pharmacology · 2020Article
- Magnolol Ameliorates Behavioral Impairments and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease.Oxidative medicine and cellular longevity · 2020Article
- Natural Products and Their Bioactive Compounds: Neuroprotective Potentials against Neurodegenerative Diseases.Evidence-based complementary and alternative medicine : eCAM · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the effect of Isorhynchophylline (IRN) on the learning and memory impairments induced by aluminum chloride (AlCl
methodsFifty male Balb-c mice (4-month-old) were randomly divided into five groups: control, AlCl
resultsThe results showed that treatment with IRN could significantly ameliorate the cognitive deficits induced by AlCl
conclusionOur findings demonstrated for the first time that IRN could alleviate learning and memory impairments induced by AlCl
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.