Evidence map›Paper›PMID 29946309›Full record

ArticleFrontiers in microbiology2018

Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus

Matxalen Vidal-García, Sergio Redrado, M Pilar Domingo, Patricia Marquina, Cristina Colmenarejo, Jacques F Meis, Antonio Rezusta, Julian Pardo, Eva M Galvez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Multiplex CRISPR/Cas9 editing of gliotoxin biosynthesis genes in Aspergillus fumigatus reduces pathogenicity in broilers.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Progress in Gliotoxin Research.Molecules (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Current and Future Pathways inAntibiotics (Basel, Switzerland) · 2023
    Review
  6. Veterinary research forum : an international quarterly journal · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Matxalen Vidal-GarcíaCentro de Investigación Biomédica de Aragón, Instituto de Investigación Sanitaria Aragón, Zaragoza, Spain.
Sergio RedradoInstituto de Carboquímica, Zaragoza, Spain.
M Pilar DomingoInstituto de Carboquímica, Zaragoza, Spain.
Patricia MarquinaInstituto de Carboquímica, Zaragoza, Spain.
Cristina ColmenarejoHospital Universitario Miguel Servet, Zaragoza, Spain.
Jacques F MeisDepartment of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands.
Antonio RezustaHospital Universitario Miguel Servet, Zaragoza, Spain.
Julian PardoCentro de Investigación Biomédica de Aragón, Instituto de Investigación Sanitaria Aragón, Zaragoza, Spain.
Eva M GalvezInstituto de Carboquímica, Zaragoza, Spain.
Instituto de Carboquímica · ESCanisius-Wilhelmina Ziekenhuis · NLFundacion Agencia Aragonesa para la Investigacion y el Desarrollo · ESHospital Universitario Miguel Servet · ESInstituto de Investigación Sanitaria Aragón · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Nevertheless, studies regarding bmGT production among common opportunistic fungi, including the

Indexed as

Aspergillus spp.biomarkerbis(methylthio)gliotoxingtmAinvasive aspergillosis

Identifiers

PMID29946309
PMCPMC6006755
OpenAlexW2803273628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.