Evidence map›Paper›PMID 29946209›Full record

ReviewDialogues in clinical neuroscience2018

The intriguing relationship between coronary heart disease and mental disorders.

Marc De Hert, Johan Detraux, Davy Vancampfort

Open access · diamondAbstract readReview
In one paragraph

Review in Dialogues in clinical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 214 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 11 pooled it
27.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 11 syntheses or guidelines pooled it, 485 citations in OpenAlex.

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  5. End-of-life care for people with severe and persistent mental illness and a life-limiting disease: An umbrella review.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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  10. Could Physical Activity Have any Role in Cardiovascular Disease Prevention in Prisoners? A Systematic Review.International journal of environmental research and public health · 2021
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154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Marc De HertDepartment of Neurosciences, KU Leuven University Psychiatric Centre, Kortenberg, Belgium, KU Leuven University of Leuven, Kortenberg, Belgium.
Johan DetrauxDepartment of Neurosciences, KU Leuven University Psychiatric Centre, Kortenberg, KU Leuven University of Leuven, Kortenberg, Belgium.
Davy VancampfortDepartment of Rehabilitation Sciences, KU Leuven University of Leuven, Leuven, Belgium, KU Leuven University of Leuven, Kortenberg, Belgium.
Huntsman (Belgium) · BEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary heart disease (CHD) and mental illness are among the leading causes of morbidity and mortality worldwide. Decades of research has revealed several, and sometimes surprising, links between CHD and mental illness, and has even suggested that both may actually cause one another. However, the precise nature of these links has not yet been clearly established. The goal of this paper, therefore, is to comprehensively review and discuss the state-of-the-art nature of the epidemiological and pathophysiological aspects of the bidirectional links between mental illness and CHD. This review demonstrates that there exists a large body of epidemiological prospective data showing that people with severe mental illness, including schizophrenia, bipolar disorder, and major depressive disorder, as a group, have an increased risk of developing CHD, compared with controls [adjusted hazard ratio (adjHR)=1.54; 95% CI: 1.30-1.82,

Indexed as

Blood PressureCoronary DiseaseHeart RateHumansMental DisordersRisk Reduction Behavioranxiety disorderbipolar disordercoronary heart diseasedepressionepidemiologymental disorderpathophysiologyposttraumatic stress disorderschizophreniasevere mental illness

Identifiers

PMID29946209
PMCPMC6016051
OpenAlexW2986628198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.