Evidence map›Paper›PMID 29946137›Full record

ArticleScientific reports2018

Neuroprotective effects of Magnoliae Flos extract in mouse hippocampal neuronal cells.

Youn Sik Jung, Jin Bae Weon, Woo Seung Yang, Gahee Ryu, Choong Je Ma

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Frontiers in pharmacology · 2025
    Article
  3. The Protective Role ofInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Mediators of inflammation · 2022
    Article
  6. Anti-Inflammatory and AntioxidantPreventive nutrition and food science · 2021
    Article
  7. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  8. Article
  9. Neuroprotective Effect of Tricyclic Pyridine Alkaloids fromAntioxidants (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Youn Sik JungDepartment of Medical Biomaterials Engineering, College of Biomedical science, Kangwon National University, Chuncheon, 200-701, Korea.
Jin Bae WeonDepartment of Medical Biomaterials Engineering, College of Biomedical science, Kangwon National University, Chuncheon, 200-701, Korea.
Woo Seung YangDepartment of Medical Biomaterials Engineering, College of Biomedical science, Kangwon National University, Chuncheon, 200-701, Korea.
Gahee RyuDepartment of Medical Biomaterials Engineering, College of Biomedical science, Kangwon National University, Chuncheon, 200-701, Korea.
Choong Je MaDepartment of Medical Biomaterials Engineering, College of Biomedical science, Kangwon National University, Chuncheon, 200-701, Korea. cjma@kangwon.ac.kr.
Kangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnoliae Flos (MF) is a traditional medicinal herb used for managing rhinitis, sinusitis and headache. The purpose of the present study was to determine the neuroprotective effect of MF against glutamate-induced oxidative stress and to assess the underlying mechanism. Glutamate is a major endogenous excitatory neurotransmitter in the brain and contributes to the development of neurodegenerative diseases by excessive activation. MF extract was subjected to a neuroprotective effect assay in HT22 mouse hippocampal cells. The mechanism underlying the neuroprotective effect of MF extract was evaluated by assaying reactive oxygen species (ROS) levels, intracellular Ca

Indexed as

AnimalsApoptosisCalciumCell LineGlutathioneHippocampusMagnoliaceaeMembrane Potential, MitochondrialMiceNeuronsNeuroprotective AgentsReactive Oxygen SpeciesCalciumGlutathioneNeuroprotective AgentsReactive Oxygen Species

Identifiers

PMID29946137
PMCPMC6018738
OpenAlexW2809224429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.