Evidence map›Paper›PMID 29946072›Full record

ArticleScientific reports2018

Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome.

María Callejo, Gema Mondejar-Parreño, Bianca Barreira, José L Izquierdo-Garcia, Daniel Morales-Cano, Sergio Esquivel-Ruiz, Laura Moreno, Ángel Cogolludo, Juan Duarte, Francisco Perez-Vizcaino

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 91 citations in OpenAlex.

  1. Review
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  8. The role of dietary fibre in lung inflammation: microbiota, metabolites, and immune crosstalk.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  9. Review
  10. Nutrients · 2025
    Article
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  15. Article
  16. Tibetan herbal medicineFrontiers in microbiology · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

María CallejoDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Gema Mondejar-ParreñoDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Bianca BarreiraDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.
José L Izquierdo-GarciaCiber Enfermedades Respiratorias (Ciberes), Madrid, Spain.
Daniel Morales-CanoDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Sergio Esquivel-RuizDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Laura MorenoDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.ORCID 0000-0001-9028-2299
Ángel CogolludoDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Juan DuarteDept of Pharmacology, Faculty of Pharmacy, University of Granada, Granada, Spain.
Francisco Perez-VizcainoDepartamento de Farmacología y Toxicología. Facultad de Medicina, Universidad Complutense de Madrid, 28040, Madrid, Spain. fperez@med.ucm.es.
Universidad Complutense de Madrid · ESSpanish National Centre for Cardiovascular Research · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have analysed whether pulmonary arterial hypertension (PAH) alters the rat faecal microbiota. Wistar rats were injected with the VEGF receptor antagonist SU5416 (20 mg/kg s.c.) and followed for 2 weeks kept in hypoxia (10% O

Indexed as

AnimalsComputational BiologyGastrointestinal MicrobiomeHemodynamicsHypertension, PulmonaryMaleRatsRats, WistarRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID29946072
PMCPMC6018770
OpenAlexW2808850726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.