Evidence map›Paper›PMID 29946052›Full record

ArticlemBio2018

Long-Term

Diane G Edmondson, Bo Hu, Steven J Norris

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 219 citations in OpenAlex.

  1. Trial
  2. Article
  3. Putative mechanisms of ocular inflammation in syphilis.Journal of ophthalmic inflammation and infection · 2026
    Review
  4. Review
  5. Article
  6. Key Considerations in Evaluating Syphilis Therapeutics.Sexually transmitted diseases · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Formal description ofInternational journal of systematic and evolutionary microbiology · 2026
    Article
  12. Review
  13. Human placental trophoblasts support sustainedbioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Article
  16. Lineage-specificbioRxiv : the preprint server for biology · 2026
    Article
  17. Article
  18. Article
  19. Frontiers in immunology · 2026
    Review
  20. Frontiers in immunology · 2026
    Article

82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Diane G EdmondsonDepartment of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Bo HuDepartment of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Steven J NorrisDepartment of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA Steven.J.Norris@uth.tmc.edu.ORCID 0000-0002-2501-8034
The University of Texas Health Science Center at Houston · US

Funding

PERSISTENCE OF CNS T PALLIDUM IN HIV INFECTIONR01NS034235 · NINDS · UNIVERSITY OF WASHINGTON · PI MARRA, CHRISTINA M · 1996 to 2018
$7.0M
Factors Affecting Treponema pallidum in vitro multiplication and gene transcriptionR21AI128494 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NORRIS, STEVEN J. · 2017 to 2018
$424k
NIAID NIH HHS R21 AI128494NINDS NIH HHS R01 NS034235
6 · The paper itself

Abstract

Investigation of

Indexed as

AnimalsCulture MediaCulture TechniquesHumansMaleRabbitsSpirochaetalesSyphilisTreponema pallidumCulture Mediacell culturecell structureelectron microscopyinfectivityphysiologyspirochetesTreponema pallidum

Identifiers

PMID29946052
PMCPMC6020297
OpenAlexW2811481829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.