Evidence map›Paper›PMID 29946049›Full record

ArticlemBio2018

The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum.

Stephanie S Lehman, Nicholas F Noriea, Karin Aistleitner, Tina R Clark, Cheryl A Dooley, Vinod Nair, Simran Jeet Kaur, M Sayeedur Rahman, Joseph J Gillespie, Abdu F Azad and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 65 citations in OpenAlex.

  1. Adaptation ofmSphere · 2026
    Article
  2. Article
  3. Hybrid capture RNA-seq defines temporal gene expression inbioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Infection and immunity · 2025
    Article
  7. Article
  8. Article
  9. mSphere · 2025
    Article
  10. Article
  11. Article
  12. crANKing up the infection: ankyrin domains inInfection and immunity · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. mBio · 2024
    Article
  17. PathogenicJournal of bacteriology · 2024
    Review
  18. Article
  19. mSphere · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Stephanie S Lehman *Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Nicholas F Noriea *Host-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA.
Karin Aistleitner *Host-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA.
Tina R ClarkHost-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA.
Cheryl A DooleyHost-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA.
Vinod NairResearch Technologies Branch, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA.
Simran Jeet KaurDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
M Sayeedur RahmanDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Joseph J GillespieDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Abdu F AzadDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Ted HackstadtHost-Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA THACKSTADT@niaid.nih.gov.ORCID 0000-0003-1367-5528
University of Maryland, Baltimore · USRocky Mountain Research (United States) · US

Funding

MURINE TYPHUS: VECTOR BIOLOGY AND TRANSMISSIONR01AI017828 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RAHMAN, MOHAMMED SAYEEDUR · 1985 to 2022
$10.2M
Rickettsia-host interface and multiple paths to invasionR01AI126853 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Mohammed Sayeedur Rahman, Oliver Voss · 2016 to 2026
$6.9M
IMMUNITY AND INFECTIONT32AI007540 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 1998 to 2018
$2.2M
Characterizing gene family expansion in an atypical bacterial secretion systemR21AI126108 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI GILLESPIE, JOSEPH J, RAHMAN, MOHAMMED SAYEEDUR · 2016 to 2017
$424k
NIAID NIH HHS R01 AI017828NIAID NIH HHS R01 AI126853NIAID NIH HHS R21 AI126108NIAID NIH HHS T32 AI007540
6 · The paper itself

Abstract

Strains of

Indexed as

AnimalsBacterial ProteinsEndoplasmic ReticulumFemaleGuinea PigsHumansProtein TransportRickettsia rickettsiiRocky Mountain Spotted FeverType IV Secretion SystemsVirulenceBacterial ProteinsType IV Secretion Systemsankyrin repeatgenomerickettsiatype IV secretionvirulence

Identifiers

PMID29946049
PMCPMC6020290
OpenAlexW2811156950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.