Evidence map›Paper›PMID 29946038›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Galectin-3 in M2 Macrophages Plays a Protective Role in Resolution of Neuropathology in Brain Parasitic Infection by Regulating Neutrophil Turnover.

Fredice O Quenum Zangbede, Arun Chauhan, Jyotika Sharma, Bibhuti B Mishra

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The role of galectins in immunity and infection.Nature reviews. Immunology · 2023
    Review
  10. Article
  11. Article
  12. Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Characterization of a novel galectin inFrontiers in microbiology · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fredice O Quenum ZangbedeDepartment of Biomedical Sciences, School of Medicine & Health Sciences, University of North Dakota, Grand Forks, North Dakota 58202.
Arun ChauhanDepartment of Biomedical Sciences, School of Medicine & Health Sciences, University of North Dakota, Grand Forks, North Dakota 58202.
Jyotika SharmaDepartment of Biomedical Sciences, School of Medicine & Health Sciences, University of North Dakota, Grand Forks, North Dakota 58202.
Bibhuti B MishraDepartment of Biomedical Sciences, School of Medicine & Health Sciences, University of North Dakota, Grand Forks, North Dakota 58202 bibhuti.mishra@med.und.edu.
University of North Dakota · US

Funding

Research CoresP20GM103442 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI Chris Jurgens · 2012 to 2026
$53.0M
Yersina perstis interactions with macrophagesP20GM113123 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BRADLEY, DAVID S. · 2016 to 2025
$19.9M
Pilot Projects CoreP30GM103329 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI GEIGER, JONATHAN DAVID · 2012 to 2016
$5.1M
Molecular mechanism of Mincle mediated NET formation:Implications for pneumonic sepsisR01AI121804 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHARMA, JYOTIKA · 2016 to 2020
$2.0M
Identification of protective proteins of Francisella using a novel comparative imR21AI107457 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI SHARMA, JYOTIKA · 2014 to 2015
$388k
Efferocytosis and neutrophil homeostasis in pneumonic sepsisR21AI136472 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI SHARMA, JYOTIKA · 2018 to 2019
$382k
Galectins as novel alarmins in salivary gland inflammationR21DE024300 · NIDCR · UNIVERSITY OF NORTH DAKOTA · PI MISHRA, BIBHUTI BHUSAN, SINGH, BRIJ B · 2015 to 2016
$382k
NIAID NIH HHS R01 AI121804NIAID NIH HHS R21 AI107457NIAID NIH HHS R21 AI136472NIDCR NIH HHS R21 DE024300NIGMS NIH HHS P20 GM103442NIGMS NIH HHS P20 GM113123NIGMS NIH HHS P30 GM103329
6 · The paper itself

Abstract

Macrophages/microglia with M2-activation phenotype are thought to play important anti-inflammatory and tissue reparative functions in the brain, yet the molecular bases of their functions in the CNS remain to be clearly defined. In a preclinical model of neurocysticercosis using brain infection with a parasite

Indexed as

AnimalsFemaleGalectin 3Macrophage ActivationMacrophagesMiceMice, Inbred C57BLMice, KnockoutNeurocysticercosisNeutrophilsGalectin 3braingalectin-3M2 macrophageneurocysticercosisneuroinflammationneutrophil turnover

Identifiers

PMID29946038
PMCPMC6067078
OpenAlexW2811061320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.