ArticleProceedings of the National Academy of Sciences of the United States of America2018
Kinetically guided radical-based synthesis of C(sp
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 131 citations in OpenAlex.
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- Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)-N coupling.Nature communications · 2025Article
- Biocompatible decarboxylative coupling enabled by N-hydroxynaphthalimide esters.Nature communications · 2025Article
- On-DNA C-H functionalization of electron-rich arenes for DNA-encoded libraries.Nature chemistry · 2025Article
- Building Block-Centric Approach to DNA-Encoded Library Design.Journal of chemical information and modeling · 2024Article
- Late-stage guanine C8-H alkylation of nucleosides, nucleotides, and oligonucleotides via photo-mediated Minisci reaction.Nature communications · 2024Article
- On-DNA hydroalkylation ofChemical science · 2023Article
- Impact of organic chemistry conditions on DNA durability in the context of DNA-encoded library technology.iScience · 2023Article
- Development of the Inverse Sonogashira Reaction for DEL Synthesis.ACS medicinal chemistry letters · 2023Article
- Photochemical Methods Applied to DNA Encoded Library (DEL) Synthesis.Accounts of chemical research · 2023Article
- Nickel-catalyzed reductive decarboxylation of fatty acids for drop-in biofuel production.RSC advances · 2022Article
- Reactivity Differences of Rieke Zinc Arise Primarily from Salts in the Supernatant, Not in the Solids.Journal of the American Chemical Society · 2022Article
- On-DNA Hydroalkylation to Introduce Diverse Bicyclo[1.1.1]pentanes and Abundant Alkyls via Halogen Atom Transfer.Journal of the American Chemical Society · 2022Article
- Metal-free deoxygenative coupling of alcohol-derived benzoates and pyridines for small molecules and DNA-encoded libraries synthesis.Chemical science · 2022Article
- Catalyst-controlled functionalization of carboxylic acids by electrooxidation of self-assembled carboxyl monolayers.Nature communications · 2022Article
- Site-specific DNA functionalization through the tetrazene-forming reaction in ionic liquids.Chemical science · 2022Article
- Universal encoding of next generation DNA-encoded chemical libraries.Chemical science · 2022Article
- Nature Chose Phosphates and Chemists Should Too: How Emerging P(V) Methods Can Augment Existing Strategies.ACS central science · 2021Review
- Photoredox-mediated hydroalkylation and hydroarylation of functionalized olefins for DNA-encoded library synthesis.Chemical science · 2021Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
Abstract
DNA-encoded libraries (DEL)-based discovery platforms have recently been widely adopted in the pharmaceutical industry, mainly due to their powerful diversity and incredible number of molecules. In the two decades since their disclosure, great strides have been made to expand the toolbox of reaction modes that are compatible with the idiosyncratic aqueous, dilute, and DNA-sensitive parameters of this system. However, construction of highly important C(sp
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.