Observational studyThe European respiratory journal2018
Prevalence, characteristics and management of frequently exacerbating asthma patients: an observational study in Sweden (PACEHR).
Observational study in The European respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Characteristics of severe asthma patients with biologic treatment in the Swedish National Airway Register.European clinical respiratory journal · 2026Article
- Hospitalization Pattern for Chronic Lower Respiratory Diseases in Australia: A Retrospective Ecological Study.Cureus · 2022Article
- Infertility, pregnancy loss and assisted reproduction in women with asthma: a population-based cohort study.Human reproduction (Oxford, England) · 2022Observational
- Age at asthma diagnosis is related to prevalence and characteristics of asthma symptoms.The World Allergy Organization journal · 2022Article
- Eosinophilic airway diseases: basic science, clinical manifestations and future challenges.European clinical respiratory journal · 2022Review
- Short-term exposure to ozone and asthma exacerbation in adults: A longitudinal study in China.Frontiers in public health · 2022Article
- Association Between a Type 2 Inflammatory Disease Burden Score and Outcomes Among Patients with Asthma.Journal of asthma and allergy · 2021Article
- Bringing asthma care into the twenty-first century.NPJ primary care respiratory medicine · 2020Review
- Overuse of short-acting βThe European respiratory journal · 2020Article
- "I did not know it was so important to take it the whole time" - self-reported barriers to medical treatment among individuals with asthma.BMC pulmonary medicine · 2019Article
- A Multicenter, Observational, Prospective Study of the Effectiveness of Switching from Budesonide/Formoterol TurbuhalerAdvances in therapy · 2019Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to investigate the prevalence, management and characteristics of asthma patients with frequent exacerbations.Data from asthma patients (aged ≥18 years) identified in primary care medical records were linked to Swedish national health registries. Exacerbations were defined as hospitalisations, emergency visits and/or collection of oral steroids. Frequent exacerbations were defined as two or more exacerbations per year during the 3-year observation period.Of 18 724 asthma patients, 81.49% had no exacerbations and 6.3% had frequent exacerbations in the year prior to the index date. Frequent exacerbations were observed yearly for 1.8% of the patients. Frequent exacerbators were older, more often females, and had increased eosinophil and neutrophil counts, lower lung function, and more comorbidities than patients without exacerbations. There was a slight increase in asthma medication claims and a slight decrease in physician visits compared with baseline, both in the group with and the group without frequent exacerbations.Patients with frequent exacerbations were characterised by greater age, female predominance, high eosinophil and neutrophil counts, and high prevalence of comorbidities. This study indicates that the Swedish healthcare system lacks efficiency to adjust treatment and management for this patient group. With new treatment options targeting severe asthma available, identification of these patients should be in focus to ensure reduction of exacerbations.
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