Evidence map›Paper›PMID 29945941›Full record

ArticleMolecular systems biology2018

Integrative multi-omics analysis of intestinal organoid differentiation.

Rik Gh Lindeboom, Lisa van Voorthuijsen, Koen C Oost, Maria J Rodríguez-Colman, Maria V Luna-Velez, Cristina Furlan, Floriane Baraille, Pascal Wtc Jansen, Agnès Ribeiro, Boudewijn Mt Burgering and 2 more

Abstract read
In one paragraph

Article in Molecular systems biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Live-Cell Calcium Imaging in 3D Intestinal Organoids.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Listen to Your Gut: Key Concepts for Bioengineering Advanced Models of the Intestine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rik Gh LindeboomDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Lisa van VoorthuijsenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Koen C OostMolecular Cancer Research, Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Maria J Rodríguez-ColmanMolecular Cancer Research, Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Maria V Luna-VelezDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Cristina FurlanDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Floriane BarailleCentre de Recherche des Cordeliers, INSERM, IHU ICAN, Sorbonne Université Université Paris Descartes, Paris, France.
Pascal Wtc JansenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Agnès RibeiroCentre de Recherche des Cordeliers, INSERM, IHU ICAN, Sorbonne Université Université Paris Descartes, Paris, France.
Boudewijn Mt BurgeringMolecular Cancer Research, Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Hugo J SnippertMolecular Cancer Research, Center for Molecular Medicine, Oncode Institute, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands h.j.g.snippert@umcutrecht.nl michiel.vermeulen@science.ru.nl.
Michiel VermeulenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands h.j.g.snippert@umcutrecht.nl michiel.vermeulen@science.ru.nl.ORCID 0000-0003-0836-6894

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal organoids accurately recapitulate epithelial homeostasis

Indexed as

Computational BiologyOrganogenesisAnimalsGene Expression RegulationIntestinesMiceOrganoidsStem Cellsadult intestinal stem cellsenterocytesHnf4gorganoidssystems biology

Identifiers

PMID29945941
PMCPMC6018986

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.