Evidence map›Paper›PMID 29945855›Full record

ArticleJMIR cancer2018

YouTube Videos as a Source of Information About Clinical Trials: Observational Study.

Grace Clarke Hillyer, Sarah A MacLean, Melissa Beauchemin, Corey H Basch, Karen M Schmitt, Leslie Segall, Moshe Kelsen, Frances L Brogan, Gary K Schwartz

Abstract read
In one paragraph

Article in JMIR cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Grace Clarke HillyerDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.ORCID http://orcid.org/0000-0003-0467-075X
Sarah A MacLeanDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.ORCID http://orcid.org/0000-0003-2324-0448
Melissa BeaucheminHerbert Irving Comprehensive Cancer Center, New York, NY, United States.ORCID http://orcid.org/0000-0003-4058-1586
Corey H BaschDepartment of Public Health, William Paterson University, Paterson, NJ, United States.ORCID http://orcid.org/0000-0003-4862-4229
Karen M SchmittNew York Presbyterian Hospital, New York, NY, United States.ORCID http://orcid.org/0000-0003-3646-6323
Leslie SegallHerbert Irving Comprehensive Cancer Center, New York, NY, United States.ORCID http://orcid.org/0000-0001-9258-6202
Moshe KelsenHerbert Irving Comprehensive Cancer Center, New York, NY, United States.ORCID http://orcid.org/0000-0002-4646-6725
Frances L BroganHerbert Irving Comprehensive Cancer Center, New York, NY, United States.ORCID http://orcid.org/0000-0002-0568-9009
Gary K SchwartzHerbert Irving Comprehensive Cancer Center, New York, NY, United States.ORCID http://orcid.org/0000-0003-1813-5061

Funding

Columbia University NCI Community Oncology Research ProgramUG1CA189960 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jennifer E. Amengual, Lisa A. Kachnic · 2014 to 2026
$12.7M
NCI NIH HHS UG1 CA189960
6 · The paper itself

Abstract

backgroundClinical trials are essential to the advancement of cancer treatment but fewer than 5% of adult cancer patients enroll in a trial. A commonly cited barrier to participation is the lack of understanding about clinical trials.

objectiveSince the internet is a popular source of health-related information and YouTube is the second most visited website in the world, we examined the content of the top 115 YouTube videos about clinical trials to evaluate clinical trial information available through this medium.

methodsYouTube videos posted prior to March 2017 were searched using selected keywords. A snowballing technique was used to identify videos wherein sequential screening of the autofill search results for each set of keywords was conducted. Video characteristics (eg, number of views and video length) were recorded. The content was broadly grouped as related to purpose, phases, design, safety and ethics, and participant considerations. Stepwise multivariable logistic regression analysis was conducted to assess associations between video type (cancer vs noncancer) and video characteristics and content.

resultsIn total, 115 videos were reviewed. Of these, 46/115 (40.0%) were cancer clinical trials videos and 69/115 (60.0%) were noncancer/general clinical trial videos. Most videos were created by health care organizations/cancer centers (34/115, 29.6%), were oriented toward patients (67/115, 58.3%) and the general public (68/115, 59.1%), and were informational (79/115, 68.7%); altruism was a common theme (31/115, 27.0%). Compared with noncancer videos, cancer clinical trials videos more frequently used an affective communication style and mentioned the benefits of participation. Cancer clinical trial videos were also much more likely to raise the issue of costs associated with participation (odds ratio [OR] 5.93, 95% CI 1.15-29.46) and advise patients to communicate with their physician about cancer clinical trials (OR 4.94, 95% CI 1.39-17.56).

conclusionsCollectively, YouTube clinical trial videos provided information on many aspects of trials; however, individual videos tended to focus on selected topics with varying levels of detail. Cancer clinical trial videos were more emotional in style and positive in tone and provided information on the important topics of cost and communication. Patients are encouraged to verify and supplement YouTube video information in consultations with their health care professionals to obtain a full and accurate picture of cancer clinical trials to make an adequately informed decision about participation.

Indexed as

cancer clinical trialclinical trialhealth informationinternetsocial mediaYouTube videos

Identifiers

PMID29945855
PMCPMC6039767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.