Evidence map›Paper›PMID 29945740›Full record

ArticlePsychiatry research. Neuroimaging2018

A longitudinal human phantom reliability study of multi-center T1-weighted, DTI, and resting state fMRI data.

Colin Hawco, Joseph D Viviano, Sofia Chavez, Erin W Dickie, Navona Calarco, Peter Kochunov, Miklos Argyelan, Jessica A Turner, Anil K Malhotra, Robert W Buchanan and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Psychiatry research. Neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Multiscale neural signatures of major depressive, anxiety, and stress-related disorders.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Structural brain networks in remitted psychotic depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Colin HawcoCampbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Joseph D VivianoCampbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada.
Sofia ChavezCampbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Erin W DickieCampbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada.
Navona CalarcoCampbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada.
Peter KochunovMaryland Psychiatric Research Center, University of Maryland School of Medicine, P.O. Box 21247, Baltimore, MD, United States.
Miklos ArgyelanZucker Hillside Hospital, 75-59 263rd St, Glen Oaks, NY, United States.
Jessica A TurnerDepartment of Psychology, Georgia State University, 33 Gilmer Street SE, Atlanta, GA, United States.
Anil K MalhotraZucker Hillside Hospital, 75-59 263rd St, Glen Oaks, NY, United States; The Zucker School of Medicine at Hofstra/Northwell.
Robert W BuchananMaryland Psychiatric Research Center, University of Maryland School of Medicine, P.O. Box 21247, Baltimore, MD, United States.
Aristotle N VoineskosCampbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Electronic address: colin.hawco@camh.ca.
SPINS Group

Funding

SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
2/3-Social Processes Initiative in Neurobiology of the Schizophrenia(s)R01MH102313 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI MALHOTRA, ANIL K · 2014 to 2018
$1.9M
3/3-Social Processes Initiative in Neurobiology of the Schizophrenia(s)R01MH102318 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI BUCHANAN, ROBERT W, CARPENTER, WILLIAM T. · 2014 to 2018
$1.7M
1/3 - Social Processes Initiative in Neurobiology of the Schizophrenia(s)R01MH102324 · NIMH · CENTRE FOR ADDICTION AND MENTAL HEALTH · PI VOINESKOS, ARISTOTLE NICHOLAS · 2014 to 2018
$1.4M
Hybrid GPU/CPU Computing Resource to Support Connectomic and GenomicsS10OD023696 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI KOCHUNOV, PETER V. · 2018 to 2018
$593k
NIBIB NIH HHS R01 EB015611NIH HHS S10 OD023696NIMH NIH HHS R01 MH102313NIMH NIH HHS R01 MH102318NIMH NIH HHS R01 MH102324
6 · The paper itself

Abstract

Multi-center MRI studies can enhance power, generalizability, and discovery for clinical neuroimaging research in brain disorders. Here, we sought to establish the utility of a clustering algorithm as an alternative to more traditional intra-class correlation coefficient approaches in a longitudinal multi-center human phantom study. We completed annual reliability scans on 'travelling human phantoms'. Acquisitions across sites were harmonized prospectively. Twenty-seven MRI sessions were available across four participants, scanned on five scanners, across three years. For each scan, three metrics were extracted: cortical thickness (CT), white matter fractional anisotropy (FA), and resting state functional connectivity (FC). For each metric, hierarchical clustering (Ward's method) was performed. The cluster solutions were compared to participant and scanner using the adjusted Rand index (ARI). For all metrics, data clustered by participant rather than by scanner (ARI > 0.8 comparing clusters to participants, ARI < 0.2 comparing clusters to scanners). These results demonstrate that hierarchical clustering can reliably identify structural and functional scans from different participants imaged on different scanners across time. With increasing interest in data-driven approaches in psychiatric and neurologic brain imaging studies, our findings provide a framework for multi-center analytic approaches aiming to identify subgroups of participants based on brain structure or function.

Indexed as

Data AnalysisAdultCerebral CortexDiffusion Tensor ImagingHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingPhantoms, ImagingReproducibility of ResultsCortical thicknessDTIFractional anisotropyFunctional connectivityHierarchical clusteringHuman phantomsMulti-sitersfMRIScanner reliabilityScanner variabilityT1

Identifiers

PMID29945740
PMCPMC6482446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.