Evidence map›Paper›PMID 29945647›Full record

ArticleReproductive health2018

Trends and determinants of stillbirth in developing countries: results from the Global Network's Population-Based Birth Registry.

Sarah Saleem, Shiyam Sunder Tikmani, Elizabeth M McClure, Janet L Moore, Syed Iqbal Azam, Sangappa M Dhaded, Shivaprasad S Goudar, Ana Garces, Lester Figueroa, Irene Marete and 18 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Reproductive health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 66 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 7 pooled it
22.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073475 recruitingnot on this map

Global Network for Women's and Children's Health Research Maternal Newborn Health Registry

TypeobservationalSponsorNICHD Global Network for Women's and Children's HealthRan2008 to 2030Enrolled950,000ConditionsPregnancy Outcome Trends in Low-resource Geographic AreasArmsThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 7 syntheses or guidelines pooled it, 128 citations in OpenAlex.

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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 13 institutions in 6 countries.

Sarah SaleemDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan. Sarah.Saleem@aku.edu.
Shiyam Sunder TikmaniDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Elizabeth M McClureRTI International, Durham, NC, USA.
Janet L MooreRTI International, Durham, NC, USA.
Syed Iqbal AzamDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Sangappa M DhadedKLE Academy of Higher Education and Research, J N Medical College Belgaum, Karnataka, India.
Shivaprasad S GoudarKLE Academy of Higher Education and Research, J N Medical College Belgaum, Karnataka, India.
Ana GarcesINCAP, Guatemala City, Guatemala.
Lester FigueroaINCAP, Guatemala City, Guatemala.
Irene MareteMoi University School of Medicine, Eldoret, Kenya.
Constance TengeMoi University School of Medicine, Eldoret, Kenya.
Fabian EsamaiMoi University School of Medicine, Eldoret, Kenya.
Archana B PatelLata Medical Research Foundation, Nagpur, India.
Sumera Aziz AliDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Farnaz NaqviDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Musaku MwenchanyaUniversity of Zambia, Lusaka, Zambia.
Elwyn ChombaUniversity of Zambia, Lusaka, Zambia.
Waldemar A CarloUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Richard J DermanThomas Jefferson University, Philadelphia, PA, USA.
Patricia L HibberdBoston University, Boston, MA, USA.
Sherri BucherIndiana University, Indianapolis, IN, USA.
Edward A LiechtyIndiana University, Indianapolis, IN, USA.
Nancy KrebsUniversity of Colorado, Denver, CO, USA.
K Michael HambidgeUniversity of Colorado, Denver, CO, USA.
Dennis D WallaceRTI International, Durham, NC, USA.
Marion Koso-ThomasNICHD, Bethesda, MD, USA.
Menachem MiodovnikNICHD, Bethesda, MD, USA.
Robert L GoldenbergColumbia University Medical Center, New York, NY, USA.
Aga Khan University · PKMoi University · KERTI International · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USIndiana University – Purdue University Indianapolis · USInstitute of Nutrition of Central America and Panama · GTKLE University · INUniversity of Colorado Denver · USUniversity of Zambia · ZMColumbia University Irving Medical Center · USLata Medical Research Foundation · INThomas Jefferson University · USUniversity of Alabama at Birmingham · US

Funding

Global Network for Women's and Children's Health Research Data Coordinating CenterU24HD092094 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI Elizabeth M McClure · 2017 to 2026
$17.8M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL, KREBS, NANCY F · 2013 to 2017
$5.1M
Columbia University/Aga Khan University Global Network Research UnitU10HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOLDENBERG, ROBERT L · 2013 to 2017
$3.2M
NICHD NIH HHS U10 HD076474NICHD NIH HHS U10 HD078438NICHD NIH HHS U24 HD092094NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

backgroundStillbirth rates remain high, especially in low and middle-income countries, where rates are 25 per 1000, ten-fold higher than in high-income countries. The United Nations' Every Newborn Action Plan has set a goal of 12 stillbirths per 1000 births by 2030 for all countries.

methodsFrom a population-based pregnancy outcome registry, including data from 2010 to 2016 from two sites each in Africa (Zambia and Kenya) and India (Nagpur and Belagavi), as well as sites in Pakistan and Guatemala, we evaluated the stillbirth rates and rates of annual decline as well as risk factors for 427,111 births of which 12,181 were stillbirths.

resultsThe mean stillbirth rates for the sites were 21.3 per 1000 births for Africa, 25.3 per 1000 births for India, 56.9 per 1000 births for Pakistan and 19.9 per 1000 births for Guatemala. From 2010 to 2016, across all sites, the mean stillbirth rate declined from 31.7 per 1000 births to 26.4 per 1000 births for an average annual decline of 3.0%. Risk factors for stillbirth were similar across the sites and included maternal age < 20 years and age > 35 years. Compared to parity 1-2, zero parity and parity > 3 were both associated with increased stillbirth risk and compared to women with any prenatal care, women with no prenatal care had significantly increased risk of stillbirth in all sites.

conclusionsAt the current rates of decline, stillbirth rates in these sites will not reach the Every Newborn Action Plan goal of 12 per 1000 births by 2030. More attention to the risk factors and treating the causes of stillbirths will be required to reach the Every Newborn Action Plan goal of stillbirth reduction.

trial registrationNCT01073475 .

Indexed as

AdultDeveloping CountriesFemaleHumansInfantInfant MortalityInfant, NewbornMaternal AgePregnancyPregnancy OutcomeRegistriesStillbirthLow-middle income countriesRates of declineStillbirth

Identifiers

PMID29945647
PMCPMC6019981
OpenAlexW2809405128

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.