ArticleEnvironmental health and preventive medicine2018
The Murakami Cohort Study of vitamin D for the prevention of musculoskeletal and other age-related diseases: a study protocol.
Article in Environmental health and preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
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- Dietary protein intake, animal-to-plant protein ratio and risk of sarcopenia in community-dwelling adults: a 9-year follow-up study.Public health nutrition · 2026Article
- Comparison of serum 25-hydroxyvitamin D levels between patients with multiple chemical sensitivity and healthy controls: A case-control study.Scientific reports · 2026Article
- Dietary magnesium intake and dementia risk in community-dwelling people aged 40-74 years: an 8-year cohort study.Journal of nutritional science · 2026Article
- Plasma 25-hydroxyvitamin D concentrations, vitamin D deficiency and mortality in community-dwelling Japanese adults.The British journal of nutrition · 2025Article
- Green tea consumption and dementia risk in community-dwelling Japanese people aged 40-74 years: A 12-year cohort study.The journal of nutrition, health & aging · 2025Article
- Physical activity and risk of sarcopenia in 6500 community-dwelling Japanese people aged 40-74 years: an 8-year follow-up study.Environmental health and preventive medicine · 2025Article
- Low plasma 25-hydroxyvitamin D levels are not associated with a high risk of recurrent falls in community-dwelling Japanese adults: the Murakami cohort study.Archives of osteoporosis · 2024Article
- Body mass index, height, and osteoporotic fracture risk in community-dwelling Japanese people aged 40-74 years.Journal of bone and mineral metabolism · 2024Article
- Urinary proteome profiles associated with cognitive decline in community elderly residents-A pilot study.Frontiers in neurology · 2023Article
- Physical activity and recurrent fall risk in community-dwelling Japanese people aged 40-74 years: the Murakami cohort study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2022Article
- Education, household income, and depressive symptoms in middle-aged and older Japanese adults.BMC public health · 2021Article
- Alterations in Glycerolipid and Fatty Acid Metabolic Pathways in Alzheimer's Disease Identified by Urinary Metabolic Profiling: A Pilot Study.Frontiers in neurology · 2021Article
- Association between standardized vitamin 25(OH)D and dyslipidemia: a community-based study in Riyadh, Saudi Arabia.Environmental health and preventive medicine · 2020Article
- Association of derived patterns of musculoskeletal disorders with psychological problems: a latent class analysis.Environmental health and preventive medicine · 2019Article
- The impact of work-related risk factors on the development of neck and upper limb pain among low wage hotel housekeepers in Gondar town, Northwest Ethiopia: institution-based cross-sectional study.Environmental health and preventive medicine · 2019Article
- Epidemiological profiles of chronic low back and knee pain in middle-aged and elderly Japanese from the Murakami cohort.Journal of pain research · 2018Article
- Molecular Network Analysis of the Urinary Proteome of Alzheimer's Disease Patients.Dementia and geriatric cognitive disorders extraArticle
- Urinary Apolipoprotein C3 Is a Potential Biomarker for Alzheimer's Disease.Dementia and geriatric cognitive disorders extraArticle
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundAge-related musculoskeletal diseases are becoming increasingly burdensome in terms of both individual quality of life and medical cost. We intended to establish a large population-based cohort study to determine environmental, lifestyle, and genetic risk factors of musculoskeletal and other age-related diseases, and to clarify the association between vitamin D status and such diseases.
methodsWe targeted 34,802 residents aged 40-74 years living in areas of northern Niigata Prefecture, including Sekikawa Village, Awashimaura Village, and Murakami City (Murakami region). The baseline questionnaire survey, conducted between 2011 and 2013, queried respondents on their lifestyle and environmental factors (predictors), and self-reported outcomes. Plasma 25-hydroxyvitamin D (25[OH]D) concentration, an indicator of vitamin D status, was determined with the Liaison® 25OH Vitamin D Total Assay. The primary outcome of this study was osteoporotic fracture; other outcomes included age-related diseases including knee osteoarthritis, perception of chronic pain, dementia, and long-term care insurance use. Mean ages of men and women were 59.2 (SD = 9.3, N = 6907) and 59.0 (SD = 9.3, N = 7457) years, respectively. From the blood samples provided by 3710 men and 4787 women, mean 25(OH)D concentrations were 56.5 (SD = 18.4) nmol/L (22.6 ng/mL) and 45.4 (SD = 16.5) nmol/L (18.2 ng/mL), respectively. DISCUSSION: Follow-up surveys are planned every 5 years for 15 years, and incident cases of our targeted diseases will be followed at hospitals and clinics in and nearby the cohort area. We anticipate that we will be able to clarify the association between vitamin D status and multiple disease outcomes in a Japanese population.
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