ArticleBMC pregnancy and childbirth2018
Nausea and vomiting during pregnancy associated with lower incidence of preterm births: the Japan Environment and Children's Study (JECS).
Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Periconception Maternal Vitamin D Status on Nausea and Vomiting Symptoms in Early Pregnancy Among Women with a History of Pregnancy Loss.Nutrients · 2026Trial
- Transient changes in body weight and behavior during the placentation period in non-human primates and rodents.Scientific reports · 2026Article
- The association of parental use of new tobacco products and combustible cigarettes with nausea and vomiting in pregnancy: a cross-sectional study.Environmental health and preventive medicine · 2026Article
- A national study on maternal vomiting during pregnancy in Iran: prevalence, determinants, adverse birth outcomes, and the trend.BMC pregnancy and childbirth · 2024Article
- Re-examining the adaptive function of nausea and vomiting in pregnancy.Evolution, medicine, and public health · 2024Article
- Nausea, vomiting and conflict in pregnancy: The adaptive significance of Growth-Differentiation Factor 15.Evolution, medicine, and public health · 2024Article
- Evaluation of nausea and vomiting in the first trimester on the risk of adverse birth outcomes and the contribution of genetic polymorphisms: a pilot prospective study.Archives of gynecology and obstetrics · 2023Article
- Article
- The NVP QOL Questionnaire: Psychometric properties of the self-report measure of health-related quality of life for nausea and vomiting during pregnancy.PCN reports : psychiatry and clinical neurosciences · 2022Article
- Severe nausea and vomiting in pregnancy: psychiatric and cognitive problems and brain structure in children.BMC medicine · 2020Article
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9 authors.
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Abstract
backgroundNausea and vomiting during pregnancy (NVP) is considered to be associated with favorable fetal outcomes, such as a decreased risk for spontaneous abortion. However, the relationship between NVP and preterm births remains unknown. This study was conducted to evaluate the association between NVP and the risk of preterm births.
methodsThe dataset of a birth cohort study, the Japan Environment and Children's Study (JECS), was retrospectively reviewed. Participants' experience of NVP prior to 12 gestational weeks were evaluated by a questionnaire administered from 22 weeks of pregnancy to 1 month before delivery. NVP responses were elicited against four choices based on which the study population was divided into four subcohorts. Preterm birth was the main study outcome. Logistic regression analysis was used to quantify an association between NVP and risk of preterm birth.
resultsOf 96,056 women, 79,460 (82.7%) experienced some symptoms of NVP and 10,518 (10.9%) experienced severe NVP. Compared to those who did not experience NVP, women with severe NVP had lower odds for preterm birth [adjusted odds ratio (aOR) 0.84, 95% confidence interval (95% CI) 0.74-0.95]. An even lower OR was found among very preterm birth and extremely preterm birth (aOR 0.44, 95% CI 0.29-0.65).
conclusionAn inverse association exists between NVP and preterm births, especially, very preterm births and extremely preterm births.
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