Evidence map›Paper›PMID 29945552›Full record

ArticleBMC genomics2018

Identification and characterization of long noncoding RNAs and mRNAs expression profiles related to postnatal liver maturation of breeder roosters using Ribo-zero RNA sequencing.

Shengru Wu, Yanli Liu, Wei Guo, Xi Cheng, Xiaochun Ren, Si Chen, Xueyuan Li, Yongle Duan, Qingzhu Sun, Xiaojun Yang

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. LncRNAs in domesticated animals: from dog to livestock species.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shengru WuCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Yanli LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Wei GuoCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Xi ChengCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Xiaochun RenDazhou Institute of Agricultural Sciences, Dazhou, 635000, Sichuan, China.
Si ChenCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Xueyuan LiCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Yongle DuanCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Qingzhu SunCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Xiaojun YangCollege of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China. yangxj@nwsuaf.edu.cn.
Northwest A&F University · CNDazhou Academy of Agricultural Sciences · CN

Funding

the National Key Research and Development Projects 2017YFD0502200, 20170500500the program for Shaanxi science & technology 2017TSCXL-NY-04-04, 2015KTCQ02-19
6 · The paper itself

Abstract

backgroundThe liver is mainly hematopoietic in the embryo, and converts into a major metabolic organ in the adult. Therefore, it is intensively remodeled after birth to adapt and perform adult functions. Long non-coding RNAs (lncRNAs) are involved in organ development and cell differentiation, likely they have potential roles in regulating postnatal liver development. Herein, in order to understand the roles of lncRNAs in postnatal liver maturation, we analyzed the lncRNAs and mRNAs expression profiles in immature and mature livers from one-day-old and adult (40 weeks of age) breeder roosters by Ribo-Zero RNA-Sequencing.

resultsAround 21,939 protein-coding genes and 2220 predicted lncRNAs were expressed in livers of breeder roosters. Compared to protein-coding genes, the identified chicken lncRNAs shared fewer exons, shorter transcript length, and significantly lower expression levels. Notably, in comparison between the livers of newborn and adult breeder roosters, a total of 1570 mRNAs and 214 lncRNAs were differentially expressed with the criteria of log

conclusionsThis study provides a catalog of mRNAs and lncRNAs related to postnatal liver maturation of chicken, and will contribute to a fuller understanding of biological processes or signaling pathways involved in significant functional transition during postnatal liver development that differentially expressed genes and lncRNAs could take part in.

Indexed as

AnimalsChickensGene Expression ProfilingLiverMaleRNA, Long NoncodingRNA, MessengerSequence Analysis, RNARNA, Long NoncodingRNA, MessengerChickenDifferential expressionLncRNAsPostnatal liver maturationTranscriptome

Identifiers

PMID29945552
PMCPMC6020324
OpenAlexW2810283585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.