Evidence map›Paper›PMID 29944781›Full record

ArticleInfluenza and other respiratory viruses2018

Risk factors for bronchiolitis severity: A retrospective review of patients admitted to the university hospital from central region of Slovenia.

Ajda Praznik, Neža Vinšek, Ana Prodan, Vanja Erčulj, Marko Pokorn, Tatjana Mrvič, Darja Paro, Uroš Krivec, Franc Strle, Miroslav Petrovec and 2 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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  12. Comparison of Kristjansson Respiratory Score and Wang Respiratory Score in infants with bronchiolitis in a hospital emergency department.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2020
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  15. Respiratory Syncytial Virus Disease Severity Is Associated with Distinct CD8American journal of respiratory and critical care medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Ajda PraznikFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Neža VinšekFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Ana ProdanFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0002-1116-2844
Vanja ErčuljRhoSigma, Ljubljana, Slovenia.
Marko PokornDepartment of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Tatjana MrvičDepartment of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Darja ParoDepartment of Neonatology, University Children's Hospital, University Medical Centre, Ljubljana, Slovenia.
Uroš KrivecPulmonology Department, University Children's Hospital, University Medical Centre, Ljubljana, Slovenia.
Franc StrleDepartment of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Miroslav PetrovecChair of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Marta Žnidaršič ErženPediatric Clinical Department, Community Health Centre Ljubljana, Ljubljana, Slovenia.
Štefan GrosekChair of Pediatrics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
University of Ljubljana · SILjubljana University Medical Centre · SICommunity Health Centre Ljubljana · SIElektro Ljubljana (Slovenia) · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimStudy's objective was to identify risk factors associated with bronchiolitis severity.

methodsA retrospective chart review of all children <2 years old diagnosed with bronchiolitis at the University Medical Centre Ljubljana between May 2014 and April 2015, who were treated as outpatients (paediatric emergency department, PED group) or as inpatients in the standard hospital setting (WARD group) or in the paediatric intensive care unit (PICU group). Detection of respiratory viruses in nasopharyngeal swab was accomplished by RT-PCR. Severity was assessed by Wang Respiratory Score and hospitalization longer than 24 hours.

resultsThe study included 761 children. The three most frequently detected viruses were respiratory syncytial virus (RSV), human rhinovirus (hRV) and human bocavirus (hBoV) (57.5%, 272/473; 25.6%, 121/473; 18.4%, 87/473). Patient groups differed in Wang Respiratory Score for the severity of bronchiolitis (P < 0.001). No differences regarding the causative viruses were found. There was a lower proportion of children with the presence of more than one virus in PICU group compared to other two groups (P = 0.017). The three groups significantly differed in age, birthweight, comorbidities, bronchodilator treatment and antibiotic usage. However, multiple regression analysis revealed that younger age and the use of antibiotics were associated with bronchiolitis severity defined as hospitalization for >24 hours.

conclusionsRespiratory syncytial virus, hRV and hBoV were the most frequently detected viruses. The majority of patients admitted to the PICU had only one virus detected. Younger age and the use of antibiotics were associated with bronchiolitis severity.

Indexed as

HospitalizationAge FactorsAnti-Bacterial AgentsBronchiolitisCritical CareFemaleHospitals, UniversityHumansInfantInfant, NewbornIntensive Care Units, PediatricMaleNasopharynxReal-Time Polymerase Chain ReactionRetrospective StudiesRisk FactorsAnti-Bacterial Agentsbronchiolitisrespiratory virusesrisk factorsRSV

Identifiers

PMID29944781
PMCPMC6185887
OpenAlexW2810582092

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.