Evidence map›Paper›PMID 29944438›Full record

ArticlePlant signaling & behavior2018

Biochemical control systems for small molecule damage in plants.

M Hüdig, J Schmitz, M K M Engqvist, V G Maurino

Abstract read
In one paragraph

Article in Plant signaling & behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M Hüdiga Plant Molecular Physiology and Biotechnology Group, Institute of Developmental and Molecular Biology of Plants , Heinrich Heine University, and Cluster of Excellence on Plant Sciences (CEPLAS) , Düsseldorf , Germany.ORCID 0000-0001-6322-9054
J Schmitza Plant Molecular Physiology and Biotechnology Group, Institute of Developmental and Molecular Biology of Plants , Heinrich Heine University, and Cluster of Excellence on Plant Sciences (CEPLAS) , Düsseldorf , Germany.ORCID 0000-0002-8817-8801
M K M Engqvistb Department of Biology and Biological engineering, Division of Systems and Synthetic Biology , Chalmers University of Technology , Gothenburg , Sweden.ORCID 0000-0003-2174-2225
V G Maurinoa Plant Molecular Physiology and Biotechnology Group, Institute of Developmental and Molecular Biology of Plants , Heinrich Heine University, and Cluster of Excellence on Plant Sciences (CEPLAS) , Düsseldorf , Germany.ORCID 0000-0002-3124-1451

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a system, plant metabolism is far from perfect: small molecules (metabolites, cofactors, coenzymes, and inorganic molecules) are frequently damaged by unwanted enzymatic or spontaneous reactions. Here, we discuss the emerging principles in small molecule damage biology. We propose that plants evolved at least three distinct systems to control small molecule damage: (i) repair, which returns a damaged molecule to its original state; (ii) scavenging, which converts reactive molecules to harmless products; and (iii) steering, in which the possible formation of a damaged molecule is suppressed. We illustrate the concept of small molecule damage control in plants by describing specific examples for each of these three categories. We highlight interesting insights that we expect future research will provide on those systems, and we discuss promising strategies to discover new small molecule damage-control systems in plants.

Indexed as

Oxidative StressPlantsReactive Oxygen SpeciesStress, PhysiologicalReactive Oxygen SpeciesAbiotic stressenzyme promiscuityglyoxalase systemmetabolic intermediatesmolecule damagereactive carbonyl speciesreactive oxygen speciesrepair systemscavenging systemssmall moleculessteering systems

Identifiers

PMID29944438
PMCPMC6103286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.