Evidence map›Paper›PMID 29944418›Full record

ArticleClinical schizophrenia & related psychoses2018

Re-titration rates after clozapine-induced neutropenia or agranulocytosis: A case report and literature review.

Mina Boazak, Benjamin Kahn, Lindsay Cox, James Ragazino, David R Goldsmith, Robert O Cotes

Open access · greenAbstract read
In one paragraph

Article in Clinical schizophrenia & related psychoses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mina BoazakDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine.
Benjamin KahnDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine.
Lindsay CoxDepartment of Psychiatry & Behavioral Sciences, University of Miami Leonard Miller School of Medicine.
James RagazinoDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine.
David R GoldsmithDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine.
Robert O CotesDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine.
Emory University · USUniversity of Miami · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Institutional Career Development CoreKL2TR002381 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Anandi Nayan Sheth · 2017 to 2026
$14.1M
NCATS NIH HHS KL2 TR002381NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

Clozapine-induced neutropenia occurs in 3-5% of individuals treated with clozapine. Current US guidelines require interruption of clozapine when the absolute neutrophil count (ANC) drops below 1000 cells/mm

Indexed as

agranulocytosisclozapineneutropeniarechallengere-titration rateschizophrenia

Identifiers

PMID29944418
PMCPMC6443488
OpenAlexW2810584546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.