ArticleJornal brasileiro de nefrologia
Initial surgical results of 500 Parathyroidectomies for Hyperparathyroidism related to chronic kidney disease - mineral and bone disorder.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Surgical management of presternal recurrence in hyperparathyroidism related to chronic kidney disease.Brazilian journal of otorhinolaryngology · 2026Article
- Ectopic parathyroid and its role in surgical failure.Einstein (Sao Paulo, Brazil) · 2025Article
- The magic mirror: a novel intraoperative monitoring method for parathyroid glands.Frontiers in endocrinology · 2023Review
- Surgical Management of Secondary Hyperparathyroidism.Kidney international reports · 2021Review
- Therapeutic efficacy of two surgical methods on the secondary hyperparathyroidism.Gland surgery · 2020Article
- Evaluation of laboratory parameters and symptoms after parathyroidectomy in dialysis patients with secondary hyperparathyroidism.Renal failure · 2019Article
- Parathyroidectomy in the treatment of BMD-DRC Brazil: many limitations, but still fundamental.Jornal brasileiro de nefrologiaArticle
- Parathyroidectomy in chronic kidney disease.Jornal brasileiro de nefrologiaArticle
- Sestamibi scan in renal parathyroidectomy: a worthwhile preoperative exam?Brazilian journal of otorhinolaryngologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSurgical treatment of hyperparathyroidism related to chronic kidney disease is a challenging procedure even for experienced parathyroid surgeons. Over the years, adjuvant techniques have been developed to assist the medical team to improve surgical outcomes. However, medical staff in poor countries have less access to these techniques and the effectiveness of surgery in this context is unclear.
objectiveverify the effectiveness of surgery for treatment of hyperparathyroidism related to chronic kidney disease without adjuvant techniques.
methodsOver a 5-years period, patients with hyperparathyroidism that had clinical therapeutic failure were evaluated for surgical treatment. Total parathyroidectomy with autograft or subtotal resection were the selected procedures. Surgeries were performed in a tertiary hospital in Brazil without the assistance of some of the adjuvant techniques that are usually applied, such as frozen section, nerve monitoring, and gamma probe. Intraoperative PTH and localization pre-operative exams were applied, but with huge restrictions.
resultsA total of 518 patients with hyperparathyroidism (128 secondary and 390 tertiary) were surgically treated. Total parathyroidectomy were performed in 81.5%, subtotal in 12.4%, and 61% of patients had a surgical failure. Of all failures, only 1.4% needed a second surgery totaling 98.6% of successful initial surgical treatment. Neck hematoma and unilateral focal fold paralysis occurred in 1.9% and 1.5%, respectively.
conclusionparathyroidectomy is a safe and reproducible surgical procedure even in the absence of adjuvant techniques.
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