Evidence map›Paper›PMID 29943994›Full record

ArticleOrganic letters2018

Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines.

Santosh Kurhade, Elmar Diekstra, Fandi Sutanto, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander Dömling

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Potent and Subtype-Selective Dopamine DJournal of medicinal chemistry · 2021
    Article
  2. Synthesis of imidazo[1,5-Beilstein journal of organic chemistry · 2020
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Santosh KurhadeDepartment of Drug Design , University of Groningen , A. Deusinglaan 1 , 9713 AV Groningen , The Netherlands.
Elmar DiekstraDepartment of Drug Design , University of Groningen , A. Deusinglaan 1 , 9713 AV Groningen , The Netherlands.
Fandi SutantoDepartment of Drug Design , University of Groningen , A. Deusinglaan 1 , 9713 AV Groningen , The Netherlands.
Katarzyna KurpiewskaJagiellonian University , Faculty of Chemistry , Gronostajowa 2 , 30-387 Krakow , Poland.
Justyna Kalinowska-TłuścikJagiellonian University , Faculty of Chemistry , Gronostajowa 2 , 30-387 Krakow , Poland.ORCID 0000-0001-7714-1651
Alexander DömlingDepartment of Drug Design , University of Groningen , A. Deusinglaan 1 , 9713 AV Groningen , The Netherlands.ORCID 0000-0002-9923-8873

Funding

Real-time discovery of inhibitors among billion compounds for preview and downloadR01GM097082 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAMACHO, CARLOS J. · 2011 to 2020
$2.5M
NIGMS NIH HHS R01 GM097082
6 · The paper itself

Abstract

A series of unprecedented tetrazole-linked imidazo[1,5- a]pyridines are synthesized from simple and readily available building blocks. The reaction sequence involves an azido-Ugi-deprotection reaction followed by an acetic anhydride-mediated N-acylation-cyclization process to afford the target heterocycle. Furthermore, the scope of the methodology was extended to diverse R

Indexed as

AcylationAnhydridesCyclizationMolecular StructurePyridinesAnhydridesPyridines

Identifiers

PMID29943994
PMCPMC6038091

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.