ArticleThe American journal of tropical medicine and hygiene2018
Zika Virus and the World Health Organization Criteria for Determining Recent Infection Using Plaque Reduction Neutralization Testing.
Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Article
- Seroprevalence of Dengue, Zika, and Chikungunya Viruses in Humans and Colocated Macaques in Thailand and Cambodia.The Journal of infectious diseases · 2025Article
- Seroprevalence of dengue, yellow fever, and related flaviviruses among the rural human population in Nguruman and Kerio Valley, Kenya.Frontiers in virology (Lausanne, Switzerland) · 2024Article
- Neurodevelopmental assessment of normocephalic children born to Zika virus exposed and unexposed pregnant people.Pediatric research · 2024Article
- Preparing for the next emerging perinatal infectious disease.Pediatric research · 2024Article
- Analysis of the serum proteome profile of wild stump-tailed macaques (Frontiers in veterinary science · 2024Article
- Ocular findings of congenital Zika virus infection with microcephaly.International ophthalmology · 2022Review
- Zika a Vector Borne Disease Detected in Newer States of India Amidst the COVID-19 Pandemic.Frontiers in microbiology · 2022Article
- Article
- What Will Happen to Biomedical Research in Low-and-Middle Income Countries in the PostCOVID-19 World?Current tropical medicine reports · 2021Review
- Zika Virus.Pathogens (Basel, Switzerland) · 2020Review
- Seroprevalence of Dengue, Zika, and Chikungunya Viruses in Wild Monkeys in Thailand.The American journal of tropical medicine and hygiene · 2020Article
- Immune outcomes of Zika virus infection in nonhuman primates.Scientific reports · 2020Article
- Serological Diagnosis of Flavivirus-Associated Human Infections.Diagnostics (Basel, Switzerland) · 2020Review
- A Novel Microfluidic Device Integrated with Chitosan-Modified Capillaries for Rapid ZIKV Detection.Micromachines · 2020Article
- Article
- Low seroprevalence of Zika virus infection among adults in Southern Taiwan.BMC infectious diseases · 2019Article
- Seroprevalence of Zika and Dengue Virus Antibodies among Migrant Workers, Taiwan, 2017.Emerging infectious diseases · 2019Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent Zika virus (ZIKV) epidemic swept across Latin America and the Caribbean, where dengue virus (DENV) is endemic. The antigenic similarities of these closely related flaviviruses left researchers and clinicians with challenges to interpret serological tests. Thirty-six women attending a prenatal clinic in Honduras and with positive DENV IgM enzyme-linked immunoabsorbent assays (ELISAs) were screened with a ZIKV immunoglobulin M ELISA, reverse transcription polymerase chain reaction for ZIKV and DENV 1-4, and plaque reduction neutralization tests (PRNTs) for ZIKV and DENV-2. Plaque reduction neutralization test results were interpreted using the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) criteria. Using the WHO criteria of a PRNT90 titer ≥ 20 and a 4-fold difference between ZIKV and DENV titers, we determined that 69.4% of samples had a recent ZIKV infection, compared with 5.6% using CDC criteria. The interpretation of ZIKV PRNTs in a DENV-endemic region is highly dependent on the choice of interpretation criteria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.