Evidence map›Paper›PMID 29943561›Full record

ArticleThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi2018

Gastrointestinal cancer risk in patients with a family history of gastrointestinal cancer.

Joo Won Chung, Jae Jun Park, Yun Jeong Lim, Jun Lee, Sun Moon Kim, Joung Ho Han, Seong Ran Jeon, Hong Sub Lee, Yong Sung Kim, Si Young Song and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Joo Won ChungDivision of Gastroenterology, National Medical Center, Seoul, Korea.
Jae Jun ParkDepartment of Medicine, The Graduate School, Yonsei University, Seoul, Korea.
Yun Jeong LimDepartment of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Jun LeeDepartment of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea.
Sun Moon KimDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Joung Ho HanDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
Seong Ran JeonDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Hong Sub LeeDepartment of Gastroenterology, Myongji Hospital, Goyang, Korea.
Yong Sung KimDepartment of Gastroenterology, Wonkwang University Hospital, Iksan, Korea.
Si Young SongDepartment of Medicine, The Graduate School, Yonsei University, Seoul, Korea.
Committee of Education and Ethics of the Korean Society of Gastrointestinal Cancer
Yonsei University · KRChosun University · KRChungbuk National University · KRDongguk University Ilsan Hospital · KRKonyang University · KRMyongji Hospital · KRSoonchunhyang University · KRWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThis study was performed to evaluate the relationship between family history of gastrointestinal (GI) cancers and incidence of any GI cancer in the Korean population.

methodsBetween January 2015 and July 2016, 711 GI cancer patients and 849 controls in 16 hospitals in Korea were enrolled. Personal medical histories, life styles, and family history of GI cancers were collected via questionnaire.

resultsThere was a significant difference in the incidence of family history of GI cancer between GI cancer patients and controls (p=0.002). Patients with family history of GI cancer tended to be diagnosed as GI cancer at younger age than those without family history (p=0.016). The family members of GI cancer patients who were diagnosed before 50 years of age were more frequently diagnosed as GI cancer before the age of 50 years (p=0.017). After adjusting for major confounding factors, age (adjusted odds ratio [AOR] 1.065, 95% confidence interval [CI]; 1.053-1.076), male gender (AOR 2.270, 95% CI; 1.618-3.184), smoking (AOR 1.570, 95% CI; 1.130-2.182), and sibling's history of GI cancer (AOR 1.973, 95% CI; 1.246-3.126) remained independently associated with GI cancers.

conclusionsGI cancer patients tended to have a first relative with a history of concordant GI cancer. Personal factors (old age and male) and lifestyle (smoking) contribute to the development of GI cancer, independently. Individuals with high risk for GI cancers may be advised to undergo screening at an earlier age.

Indexed as

FamilyAdultAgedCase-Control StudiesDietFemaleGastrointestinal NeoplasmsHumansLife StyleMaleMiddle AgedOdds RatioRepublic of KoreaRisk FactorsSurveys and QuestionnairesGastrointestinal neoplasmMedical history takingRisk factors

Identifiers

PMID29943561
PMCPMC12285825
OpenAlexW2810800584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.