ReviewCurrent osteoporosis reports2018
Part II: Temporomandibular Joint (TMJ)-Regeneration, Degeneration, and Adaptation.
Review in Current osteoporosis reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Effectiveness of treatments for temporomandibular joint osteoarthritis: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Temporomandibular disorder prevalence in malocclusion patients: a meta-analysis.Head & face medicine · 2025Pooled it
- Patient-Reported Quality of Life versus Physical Examination in Treating Temporomandibular Disorders with Intra-Articular Platelet-Rich Plasma Injections: An Open-Label Clinical Trial.International journal of environmental research and public health · 2022Trial
- Evaluation of IHH, PTCH1, and SMO protein immunohistochemistry in the human mandibular condyle at fetal stages from 30 to 80 mm greatest length.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Article
- Optimal IFN-γ Priming and Therapeutic Efficacy of 3D-Cultured Human Umbilical Cord-Derived Mesenchymal Stem Cells.Tissue engineering and regenerative medicine · 2026Article
- Condylar alteration in three subtypes of temporomandibular disorder based on U-HRCT: a cross-sectional study.BMC oral health · 2025Article
- Chewing loads alter TMJ metabolism and Zn homeostasis via PIEZO1/ TRPV4.Journal of biological engineering · 2025Article
- Mechanistic Insights Into Overloading-Induced Terminal Differentiation of TMJ Condylar Cartilage at the Single Cell Level.Smart medicine · 2025Article
- Assessment of Condylar Position and Its Association with Unilateral TMD in Patients with Angle's Class I, II, and III Malocclusions Using CBCT.Journal of pharmacy & bioallied sciences · 2024Article
- Diagnostic Efficacy of Bone SPECT Techniques in Differentiating Unilateral and Bilateral Condylar Hyperplasia.Diagnostics (Basel, Switzerland) · 2024Article
- Temporomandibular disorders among Ehlers-Danlos syndromes: a narrative review.The Journal of international medical research · 2024Review
- Three-dimensional evaluation of condylar morphology after orthodontic treatment in adult patients with Class II malocclusion by cone-beam computed tomography.BMC oral health · 2024Article
- Sociodemographic Profile: A Forgotten Factor in Temporomandibular Disorders? A Scoping Review.Journal of pain research · 2024Article
- Three-dimensional relationships between condylar volume and dentoskeletal characteristics in Class II hyperdivergent female adults.BMC oral health · 2023Article
- Positional Features of the Mandibular Condyle in Patients with Facial Asymmetry.Diagnostics (Basel, Switzerland) · 2023Article
- Masticatory Function in Individuals with Temporomandibular Disorders: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2023Review
- How Confinement and Back to Normal Affected the Well-Being and Thus Sleep, Headaches and Temporomandibular Disorders.International journal of environmental research and public health · 2023Article
- Evolution and development of the mammalian jaw joint: Making a novel structure.Evolution & development · 2023Review
- Repair and remodeling of the mandibular head of the condylar process in four immature dogs.Frontiers in veterinary science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewElucidate temporomandibular joint (TMJ) development and pathophysiology relative to regeneration, degeneration, and adaption. RECENT
findingsThe pharyngeal arch produces a highly conserved stomatognathic system that supports airway and masticatory function. An induced subperiosteal layer of fibrocartilage cushions TMJ functional and parafunctional loads. If the fibrocartilage disc is present, a fractured mandibular condyle (MC) regenerates near the eminence of the fossa via a blastema emanating from the medial periosteal surface of the ramus. TMJ degenerative joint disease (DJD) is a relatively painless osteoarthrosis, resulting in extensive sclerosis, disc destruction, and lytic lesions. Facial form and symmetry may be affected, but the residual bone is vital because distraction continues to lengthen the MC with anabolic bone modeling. Extensive TMJ adaptive, healing, and regenerative potential maintains optimal, life support functions over a lifetime. Unique aspects of TMJ development, function, and pathophysiology may be useful for innovative management of other joints.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.