Evidence map›Paper›PMID 29943122›Full record

ArticlePharmaceutical research2018

Chemotherapeutic Delivery from a Self-Assembling Peptide Nanofiber Hydrogel for the Management of Glioblastoma.

Christina Karavasili, Emmanuel Panteris, Ioannis S Vizirianakis, Sotirios Koutsopoulos, Dimitrios G Fatouros

Abstract read
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In one paragraph

Article in Pharmaceutical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 46 citations in OpenAlex.

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  15. Injectable biomaterials for treatment of glioblastoma.Advanced materials interfaces · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Christina KaravasiliSchool of Pharmacy, Department of Pharmaceutical Technology, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece.
Emmanuel PanterisDepartment of Botany, School of Biology, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece.
Ioannis S VizirianakisSchool of Pharmacy, Laboratory of Pharmacology, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece.
Sotirios KoutsopoulosCenter for Biomedical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
Dimitrios G FatourosSchool of Pharmacy, Department of Pharmaceutical Technology, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece. dfatouro@pharm.auth.gr.
Aristotle University of Thessaloniki · GRMassachusetts Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLocalized chemotherapy has gained significant impetus for the management of malignant brain tumors. In the present study, we appraised the versatility of an in-situ gel forming self-assembling peptide, ac-(RADA)

methodsThe morphology and mechanical properties of ac-(RADA)

resultsSEM studies revealed that the ac-(RADA)

conclusionsThe current findings highlight the potential utility of the in-situ depot forming ac-(RADA)

Indexed as

Antineoplastic AgentsApoptosisBrain NeoplasmsCell Line, TumorCurcuminDoxorubicinDrug CarriersDrug LiberationGlioblastomaHumansHydrogelsNanofibersPeptidesAntineoplastic AgentsCurcuminDoxorubicinDrug CarriersHydrogelsPeptidescancer treatmentcurcumindoxorubicindrug deliveryself-assembly

Identifiers

PMID29943122
OpenAlexW2811002634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.