ArticleSurgical endoscopy2018
Role of indo-cyanine green (ICG) fluorescence in laparoscopic adrenalectomy: a retrospective review of 55 Cases.
Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Laparoscopic Adrenal Compartment Resection for Paediatric Adrenal Neoplasms: Surgical Technique and Single-Centre Experience.European journal of haematology · 2026Article
- Application of indocyanine green fluorescence imaging in cortical-sparing adrenalectomy: a preliminary study with image quantification techniques.Surgical endoscopy · 2026Article
- Robot-Assisted Laparoscopic Partial Adrenalectomy Utilizing Intraoperative Indocyanine Green Near-Infrared Fluorescence Imaging for Pheochromocytoma: A Case Report.IJU case reports · 2026Article
- Near-Infrared Fluorescence Guidance With Indocyanine Green in Adrenal-Sparing Surgery: A Systematic Review.Cureus · 2026Review
- Indocyanine green (ICG) fluorescence in laparoscopic adrenalectomy: categorization of adrenal tumors relative to normal adrenal gland.Updates in surgery · 2026Article
- Impact of indocyanine green on decision making for performing laparoscopic cortical sparing adrenalectomy.Updates in surgery · 2024Article
- Imaging guided adrenalectomy with Indocyanine green fluorescence in a dog with a pheochromocytoma.Journal of veterinary science · 2024Article
- Characterization of indocyanine green fluorescence imaging patterns of pheochromocytomas.Surgical endoscopy · 2023Article
- Exploring the Applications of Indocyanine Green in Robot-Assisted Urological Surgery: A Comprehensive Review of Fluorescence-Guided Techniques.Sensors (Basel, Switzerland) · 2023Review
- Minimally Invasive Management of Hemorrhagic Pheochromocytoma-A Rare Case Report.Surgery journal (New York, N.Y.) · 2023Article
- Operative approach and case volume are associated with negative resection margins for adrenocortical carcinoma.Surgical endoscopy · 2022Article
- Cancer risk in adrenalectomy: are adrenal lesions equal or more than 4 cm a contraindication for laparoscopy?Surgical endoscopy · 2022Article
- A visual quantification of tissue distinction in robotic transabdominal lateral adrenalectomy: comparison of indocyanine green and conventional views.Surgical endoscopy · 2022Article
- Robotic approach for partial adrenalectomy.Updates in surgery · 2021Article
- Comparison of indocyanine green and carbon nanoparticles in endoscopic techniques for central lymph nodes dissection in patients with papillary thyroid cancer.Surgical endoscopy · 2020Article
- Indocyanine green fluorescence imaging for robotic adrenalectomy.Gland surgery · 2020Review
- Indocyanine green fluorescence imaging during partial adrenalectomy.Surgical endoscopy · 2020Article
- Fluorescence-enabled assessment of adrenal gland localization and perfusion in posterior retroperitoneoscopic adrenal surgery in a preclinical model.Surgical endoscopy · 2020Article
- Are Adrenal Lesions of 6 cm or More in Diameter a Contraindication to Laparoscopic Adrenalectomy? A Case-Control Study.World journal of surgery · 2020Article
- Fluorescence techniques in adrenal surgery.Gland surgery · 2019Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndo-Cyanine Green Fluorescence is an emerging technology with more frequent use in laparoscopic and robotic surgery. It relies on near-infrared (NIR) fluorescence to demonstrate tissue perfusion with demarcation of tissue planes and vascular pedicles. The aim of the study is to evaluate the role of this technology in laparoscopic adrenalectomy (LA).
methods55 patients underwent laparoscopic adrenalectomy using NIR Fluorescence enabled laparoscope. All cases received a standard initial dose of 5-mg dye to aid tissue visualization. Surgery proceeded with "fluorescence mode" demonstrating real-time NIR images superimposed on standard white-light imaging. The timing, number of doses were dictated by the operating surgeon, which were recorded and correlated with intra-operative fluorescence visualization.
results54 patients underwent successful LA, with one conversion in a case of large pheochromocytoma due to difficult hemostasis. The lag between ICG administration and visualization of adrenal fluorescence varied between 30 and 75 s. The total duration of adrenal parenchymal fluorescence after a single dose did not exceed 15 min in our series. Average total administered dose was 14.4 mg. We suffered no mortality. There were no adverse effects due to the dye. 5 patients suffered Grade I complications, with one patient suffering Grade II and IV complication each, as per Clavien-Dindo Classification. Final histopathology demonstrated pheochromocytoma, adrenocortical adenoma, adrenocortical carcinoma, cushing's adenoma, aldosteronoma, and myelolipoma.
conclusionWe describe our initial positive experience with ICG fluorescence in LA, with a detailed description of dye administration in our study. The technology offers real-time differentiation of tissues and identification of vascular structures, providing immediate guidance during surgery. Further evaluation of its role in adrenocortical malignancy is warranted. NIR fluorescence is a safe, useful addition in laparoscopic adrenalectomy which will undergo further refinement over time.
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