Evidence map›Paper›PMID 29942990›Full record

ArticleMolecular imaging and biology2019

In Vivo Evaluation of Magnetic Targeting in Mice Colon Tumors with Ultra-Magnetic Liposomes Monitored by MRI.

Caroline J Thébault, Grégory Ramniceanu, Aude Michel, Claire Beauvineau, Christian Girard, Johanne Seguin, Nathalie Mignet, Christine Ménager, Bich-Thuy Doan

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Caroline J ThébaultChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France.
Grégory RamniceanuChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France.
Aude MichelUPMC Univ Paris 06, CNRS UMR 8234, Laboratoire PHENIX, Case 51, Sorbonne Universités, 4 place Jussieu, 75005, Paris, France.
Claire BeauvineauChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France.
Christian GirardChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France.
Johanne SeguinChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France.
Nathalie MignetChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France.
Christine MénagerUPMC Univ Paris 06, CNRS UMR 8234, Laboratoire PHENIX, Case 51, Sorbonne Universités, 4 place Jussieu, 75005, Paris, France. christine.menager@upmc.fr.
Bich-Thuy DoanChimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), PSL Research University, 75005, Paris, France. bich-thuy.doan@chimie-paristech.fr.
Délégation Paris 5 · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe development of theranostic nanocarriers as an innovative therapy against cancer has been improved by targeting properties in order to optimize the drug delivery to safely achieve its desired therapeutic effect. The aim of this paper is to evaluate the magnetic targeting (MT) efficiency of ultra-magnetic liposomes (UML) into CT26 murine colon tumor by magnetic resonance imaging (MRI). PROCEDURES: Dynamic susceptibility contrast MRI was applied to assess the bloodstream circulation time. A novel semi-quantitative method called %I

resultsThis innovative method of processing MRI images showed the MT efficiency by a %I

conclusionsWe have developed a method that allows a semi-quantitative evaluation of targeting efficiency in tumors, which could be applied to different T

Indexed as

Magnetic Resonance ImagingMagneticsAnimalsCell Line, TumorCell SurvivalColonic NeoplasmsFemaleLiposomesLiverMagnetite NanoparticlesMiceMice, Inbred BALB CNIH 3T3 CellsLiposomesMagnetite NanoparticlesImage analysis methodLiposomeMagnetic nanoparticleMagnetic targetingMRITumor

Identifiers

PMID29942990
OpenAlexW2811427354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.