Evidence map›Paper›PMID 29942988›Full record

ReviewMolecular imaging and biology2019

Fluorescence Guidance in Surgical Oncology: Challenges, Opportunities, and Translation.

Madeline T Olson, Quan P Ly, Aaron M Mohs

Abstract readReview
In one paragraph

Review in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Intraoperative Tumor Detection Using Pafolacianine.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madeline T OlsonEppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Quan P LyFred and Pamela Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Aaron M MohsFred and Pamela Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA. aaron.mohs@unmc.edu.ORCID http://orcid.org/0000-0002-9353-5404

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Apar Kishor Ganti · 1985 to 2026
$55.0M
Project 9 - Renal Drug Targeting for the Treatment of Lupus NephritisP20GM103480 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BRONICH, TATIANA K · 2012 to 2017
$13.3M
CHEMICAL CARCINOGENESIS &CANCER BIOLOGYT32CA009476 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Jennifer D. Black · 1988 to 2026
$6.2M
Hyaluronic Acid Based Nanoparticles for Targeted Image-Guided Tumor SurgeryR01EB019449 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MOHS, AARON M. · 2014 to 2017
$1.3M
Nanotechnology for Minimally Invasive Cancer Detection and ResectionR00CA153916 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MOHS, AARON M. · 2012 to 2014
$708k
NCI NIH HHS P30 CA036727NCI NIH HHS R00 CA153916NCI NIH HHS T32 CA009476NIBIB NIH HHS R01 EB019449NIGMS NIH HHS P20 GM103480
6 · The paper itself

Abstract

Surgical resection continues to function as the primary treatment option for most solid tumors. However, the detection of cancerous tissue remains predominantly subjective and reliant on the expertise of the surgeon. Surgery that is guided by fluorescence imaging has shown clinical relevance as a new approach to detecting the primary tumor, tumor margins, and metastatic lymph nodes. It is a technique to reduce recurrence and increase the possibility of a curative resection. While significant progress has been made in developing this emerging technology as a tool to assist the surgeon, further improvements are still necessary. Refining imaging agents and tumor targeting strategies to be a precise and reliable surgical strategy is essential in order to translate this technology into patient care settings. This review seeks to provide a comprehensive update on the most recent progress of fluorescence-guided surgery and its translation into the clinic. By highlighting the current status and recent developments of fluorescence image-guided surgery in the field of surgical oncology, we aim to offer insight into the challenges and opportunities that require further investigation.

Indexed as

Surgery, Computer-AssistedSurgical OncologyTranslational Research, BiomedicalFluorescenceHumansNeoplasmsOptical ImagingFluorescenceImage-guided surgeryOptical contrast agentsOptical surgical navigationSurgical oncology

Identifiers

PMID29942988
PMCPMC6724738

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.